Evidence map›Paper›PMID 38982732›Full record

ReviewBiomarkers in medicine2024

Long noncoding RNA MALAT1 in dermatologic disorders: a comprehensive review.

Dayanara Ruiz-Ojeda, Carlos A Guzmán-Martín, Rafael Bojalil, Ximena F Balderas, Iris S Paredes-González, Javier González-Ramírez, Enrique Torres-Rasgado, Adrián Hernández-DíazCouder, Rashidi Springall, Fausto Sánchez-Muñoz

Abstract readReview
In one paragraph

Review in Biomarkers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dayanara Ruiz-OjedaPosgrado en Medicina Interna, Hospital Central Sur de Alta Especialidad de Petróleos Mexicanos, Ciudad de México, C.P. 14140, México.ORCID 0009-0007-0704-9316
Carlos A Guzmán-MartínDoctorado en Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana, Ciudad de México, C.P. 04960, México.ORCID 0000-0001-7365-9023
Rafael BojalilDepartamento de Atención a la Salud, Universidad Autónoma Metropolitana-Xochimilco, Ciudad de México, C.P. 04960, México.ORCID 0000-0002-5806-3675
Ximena F BalderasDepartamento de Inmunología, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, C.P. 14080, México.ORCID 0009-0004-7424-163X
Iris S Paredes-GonzálezDepartamento de Patología Experimental, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, C.P. 14080, México.ORCID 0000-0001-8093-7060
Javier González-RamírezLaboratorio de Biología Celular, Facultad de Enfermería, Universidad Autónoma de Baja California Campus Mexicali, Mexicali, Baja California, C.P. 21376, México.ORCID 0000-0002-7541-8773
Enrique Torres-RasgadoFacultad de Medicina, Cuerpo Académico de Medicina Interna (CA-160), Benemérita Universidad Autónoma de Puebla, Puebla, C.P. 72000,México.ORCID 0000-0001-5273-4522
Adrián Hernández-DíazCouderUnidad de Investigación Médica en Bioquímica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México, C.P. 06720, México.ORCID 0000-0001-6569-2851
Rashidi SpringallDepartamento de Inmunología, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, C.P. 14080, México.
Fausto Sánchez-MuñozDepartamento de Inmunología, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, C.P. 14080, México.ORCID 0000-0001-6556-1632

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dermatologic disorders, affecting the integumentary system, involve diverse molecular mechanisms such as cell proliferation, apoptosis, inflammation and immune responses. Long noncoding RNAs, particularly Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1), are crucial regulators of gene expression. MALAT1 influences inflammatory responses, immune cell function and signaling pathways, impacting various physiological and pathological processes, including dermatologic disorders. Dysregulation of MALAT1 is observed in skin conditions like psoriasis, atopic dermatitis and systemic lupus erythematosus. However, its precise role remains unclear. This review consolidates knowledge on MALAT1's impact on skin biology and pathology, emphasizing its potential diagnostic and therapeutic implications in dermatologic conditions.

Indexed as

RNA, Long NoncodingSkin DiseasesAnimalsDermatitis, AtopicHumansPsoriasisMALAT1 long non-coding RNA, humanRNA, Long Noncodingdermatologylong noncoding RNAsMALAT1signaling pathwaysskin disorders

Identifiers

PMID38982732
PMCPMC11497971

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.