← GLP-1 receptor agonists × kidney outcomes

Observational studyFrontiers in endocrinology2024

Effectiveness and safety of once-weekly semaglutide: findings from the SEMACOL-REAL retrospective multicentric observational study in Colombia.

Daisy C Buenaventura-Collazos et al.PubMed ↗Full text ↗Publisher ↗

What moved togetherboth groups pooled, not the treatment’s effect

Correlation, not cause

Went with lower kidney outcomes

−1.47percentage points−1.76 to −1.17

As reported

difference −1.47 %, 95% CI −1.76 to −1.17

Correlation, not cause

Went with lower glycemic control

−4.23kg−5.34 to −3.12

As reported

difference −4.23 kg, 95% CI −5.34 to −3.12

Two numbers in the abstract

the abstract, start to end

… with a mean reduction in HbA1C of -1.47% (95% CI -1.76, -1.17), weight loss of -4.23 kg (95% CI -5.34, -3.12), and …

← favours treatmentfavours comparator →
could be chance
Kidney outcomes
−1.47−1.76 to −1.17
Glycemic control
−4.23−5.34 to −3.12
GLP-1 receptor agonistsGlycemic controlKidney outcomes
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Full record →Abstract, authors, funding and every citing paper · PMID 38982987