Evidence map›Paper›PMID 38983848›Full record

ArticleFrontiers in immunology2024

Using adjusted local assortativity with Molecular Pixelation unveils colocalization of membrane proteins with immunological significance.

Jan Rhomberg-Kauert, Max Karlsson, Divya Thiagarajan, Tomasz Kallas, Filip Karlsson, Simon Fredriksson, Johan Dahlberg, Alvaro Martinez Barrio

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jan Rhomberg-KauertPixelgen Technologies AB, Stockholm, Sweden.
Max KarlssonPixelgen Technologies AB, Stockholm, Sweden.
Divya ThiagarajanPixelgen Technologies AB, Stockholm, Sweden.
Tomasz KallasPixelgen Technologies AB, Stockholm, Sweden.
Filip KarlssonPixelgen Technologies AB, Stockholm, Sweden.
Simon FredrikssonPixelgen Technologies AB, Stockholm, Sweden.
Johan DahlbergPixelgen Technologies AB, Stockholm, Sweden.
Alvaro Martinez BarrioPixelgen Technologies AB, Stockholm, Sweden.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Advances in spatial proteomics and protein colocalization are a driving force in the understanding of cellular mechanisms and their influence on biological processes. New methods in the field of spatial proteomics call for the development of algorithms and open up new avenues of research. The newly introduced Molecular Pixelation (MPX) provides spatial information on surface proteins and their relationship with each other in single cells. This allows for

Indexed as

Membrane ProteinsAlgorithmsB-LymphocytesHumansProteomicsRituximabSingle-Cell AnalysisT-LymphocytesMembrane ProteinsRituximabgraph theorylocal assortativitymolecular pixelationRituximabsingle cellspatial proteomicstopological data analysisuropod formation

Identifiers

PMID38983848
PMCPMC11231075

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.