ArticleFrontiers in neurology2024
Depressive symptoms in children and adolescents with epilepsy and primary headache: a cross-sectional observational study.
Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Beyond social media time: online self-disclosure, depressive symptoms, somatic complaints, and suicidal ideation in adolescents.Frontiers in psychiatry · 2026Article
- Probiotics and the Gut-Brain Axis: Emerging Therapeutic Strategies for Epilepsy and Depression Comorbidity.Foods (Basel, Switzerland) · 2025Review
- Psychiatric Co-Morbidities Among Children and Adolescents With Headache: Findings From a Cross-Sectional Study in Bangladesh.Brain and behavior · 2025Article
- Efficacy of prophylactic sodium valproate in pediatric migraines: a systematic review of randomized clinical studies.Translational pediatrics · 2024Review
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Authors and funding
10 authors.
Funding
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Abstract
Background: The primary aims of our cross-sectional observational study were: (i) to determine the prevalence of depressive symptoms in children and adolescents with epilepsy compared to controls and (ii) to explore the difference in depressive symptoms in patients with epilepsy only and those with epilepsy and primary headache as a comorbidity. The secondary objective was to explore parental stress levels. Methods: 68 pediatric patients aged 6-18 years (44 with epilepsy only and 24 with epilepsy and headache) and 50 controls were recruited. Depressive profile and parental stress were assessed using Children's Depression Inventory, Second Edition (CDI-2) and Parenting Stress Index-Short Form (PSI-SF). Results: The group with epilepsy showed significantly high depressive symptoms and parental stress compared to controls. The patients with headache in comorbidity experienced more depressive symptoms than those with epilepsy only. Conclusion: Depressive symptoms are more prevalent in patients who have comorbid epilepsy and primary headache; therefore, the neurological/psychological mechanisms underlying this condition should be further investigated. The simultaneous presence of epilepsy, headache and depressive symptoms impacts the quality of life of patients and their parents, increasing parental stress and family management.
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