Evidence map›Paper›PMID 38984084›Full record

ArticleWorld journal of virology2024

Exploring the impact of rotavirus vaccination on antibiotic prescription and resistance: A comprehensive systematic review.

Lakshmi Venkata Simhachalam Kutikuppala, Matei-Alexandru Cozma, Gautam Maddineni, Harshal Prakash Chorya, Nayanika Tummala, Swathi Godugu, Jyothi Swaroop Chintala, Mihnea-Alexandru Găman

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In one paragraph

Article in World journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lakshmi Venkata Simhachalam KutikuppalaDepartment of General Surgery, Dr NTR University of Health Sciences, Vijayawada 520008, Andhra Pradesh, India.
Matei-Alexandru CozmaFaculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest 050474, Romania.
Gautam MaddineniDepartment of Internal Medicine, Florida State University, Cape Coral, FL 33909, United States.
Harshal Prakash ChoryaDepartment of Internal Medicine, Baroda Medical College, Vadodara 390001, Gujarat, India.
Nayanika TummalaDepartment of Internal Medicine, GITAM Institute of Medical Sciences and Research (GIMSR), Visakhapatnam 530045, Andhra Pradesh, India.
Swathi GoduguDepartment of Internal Medicine, Zaporozhye State Medical University, Zaporozhye 69000, Ukraine.
Jyothi Swaroop ChintalaDepartment of Anesthesiology, Dr NTR University of Health Sciences, Vijayawada 520008, Andhra Pradesh, India.
Mihnea-Alexandru GămanFaculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest 050474, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRotavirus is a highly contagious virus responsible for a significant burden of acute gastroenteritis, particularly among infants and young children worldwide, however, vaccination against this viral agent is available. Several studies have hypothesized that rotavirus vaccination has been linked to lower rates of antibiotic resistance.

aimTo assess the relationship between rotavirus vaccination and antibiotic resistance.

methodsThe present systematic review was tailored based on the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. Several electronic databases (PubMed/MEDLINE, Scopus and Web of Science) were searched independently by two investigators in order to retrieve relevant publications published until April 2023 that investigated the aforementioned research question.

resultsThe comprehensive database search identified a total of 91 records. After the duplicates were removed (

conclusionIn conclusion, all the studies support the idea that vaccinations can reduce the need for antibiotic prescriptions which could potentially contribute to mitigating antibiotic resistance. However, to fully comprehend the mechanisms of antibiotic resistance, enhance treatment guidelines, and consider diverse demographic situations, further research is necessary to use evidence-based strategies to fight antibiotic misuse and resistance.

Indexed as

Antibiotic resistanceAntibioticsChildrenDiarrheaGastroenteritisRotavirusVaccination

Identifiers

PMID38984084
PMCPMC11229841

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.