Evidence mapPaperPMID 38987200Full record

ArticlePhysiological reports2024

Fast and slow myofiber nuclei, satellite cells, and size distribution with lifelong endurance exercise in men and women.

Cristhian F Montenegro, Chad Skiles, Dillon J Kuszmaul, Aaron Gouw, Kiril Minchev, Toby L Chambers, Ulrika Raue, Todd A Trappe, Scott Trappe

Abstract read
In one paragraph

Article in Physiological reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cristhian F MontenegroHuman Performance Laboratory, Ball State University, Muncie, Indiana, USA.
Chad SkilesHuman Performance Laboratory, Ball State University, Muncie, Indiana, USA.
Dillon J KuszmaulHuman Performance Laboratory, Ball State University, Muncie, Indiana, USA.
Aaron GouwHuman Performance Laboratory, Ball State University, Muncie, Indiana, USA.
Kiril MinchevHuman Performance Laboratory, Ball State University, Muncie, Indiana, USA.
Toby L ChambersHuman Performance Laboratory, Ball State University, Muncie, Indiana, USA.
Ulrika RaueHuman Performance Laboratory, Ball State University, Muncie, Indiana, USA.
Todd A TrappeHuman Performance Laboratory, Ball State University, Muncie, Indiana, USA.ORCID https://orcid.org/0000-0002-0609-5632
Scott TrappeHuman Performance Laboratory, Ball State University, Muncie, Indiana, USA.ORCID https://orcid.org/0000-0002-6438-431X

Funding

Ball State University (BSU) Human Bioenergetics ProgramHHS | NIH | National Institute on Aging (NIA) R01-AG038576
6 · The paper itself

Abstract

We previously observed lifelong endurance exercise (LLE) influenced quadriceps whole-muscle and myofiber size in a fiber-type and sex-specific manner. The current follow-up exploratory investigation examined myofiber size regulators and myofiber size distribution in vastus lateralis biopsies from these same LLE men (n = 21, 74 ± 1 years) and women (n = 7, 72 ± 2 years) as well as old, healthy nonexercisers (OH; men: n = 10, 75 ± 1 years; women: n = 10, 75 ± 1 years) and young exercisers (YE; men: n = 10, 25 ± 1 years; women: n = 10, 25 ± 1 years). LLE exercised ~5 days/week, ~7 h/week for the previous 52 ± 1 years. Slow (myosin heavy chain (MHC) I) and fast (MHC IIa) myofiber nuclei/fiber, myonuclear domain, satellite cells/fiber, and satellite cell density were not influenced (p > 0.05) by LLE in men and women. The aging groups had ~50%-60% higher proportion of large (>7000 μm

Indexed as

ExerciseMuscle Fibers, Fast-TwitchMuscle Fibers, Slow-TwitchPhysical EnduranceSatellite Cells, Skeletal MuscleAdultAgedAgingCell NucleusFemaleHumansMaleMyosin Heavy ChainsQuadriceps MuscleYoung AdultMyosin Heavy Chainsagingcross‐sectional areafiber type specificmasters athletesmyonucleisatellite cells

Identifiers

PMID38987200
PMCPMC11236482

What Socratic holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.