Evidence map›Paper›PMID 38987445›Full record

ArticleDigestive diseases and sciences2024

Hypertriglyceridemia, Hypercholesterolemia, Body Mass Index, and the Risk of Acute Pancreatitis.

Qiu Sun, Liming Du, Qingshuai Ren, Guoling Zhu, Bing Zhang, Afang Su, Shouling Wu, Shuohua Chen

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Article in Digestive diseases and sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qiu SunDepartment of Hepatobiliary, Kailuan General Hospital, No.57 Xinhua East Street, Tangshan, 063000, China. sunqiu280@tmu.edu.com.ORCID http://orcid.org/0000-0002-5798-0682
Liming DuDepartment of Traditional Chinese Medicine, Kailuan General Hospital, No.57 Xinhua East Street, Tangshan, 063000, China.
Qingshuai RenDeparment of Cardiovascular Surgery, North China University of Science and Technology Affiliated Hospital, Tangshan, 063000, China.
Guoling ZhuDepartment of Gastroenterology, Kailuan General Hospital, No.57 Xinhua East Street, Tangshan, 063000, China.
Bing ZhangDepartment of Hepatobiliary, Kailuan General Hospital, No.57 Xinhua East Street, Tangshan, 063000, China.
Afang SuDepartment of Gastroenterology, Kailuan General Hospital, No.57 Xinhua East Street, Tangshan, 063000, China.
Shouling WuDepartment of Cardiology, Kailuan General Hospital, North China University of Science and Technology, No.57 Xinhua East Street, Tangshan, 063000, China.
Shuohua ChenDepartment of Cardiology, Kailuan General Hospital, North China University of Science and Technology, No.57 Xinhua East Street, Tangshan, 063000, China.

Funding

Hebei Traditional Chinese Medicine Scientific Research Project 2023223
6 · The paper itself

Abstract

objectiveThe purpose of this work was to check the connection between parameters of lipid profile and body mass index (BMI) in relation to the occurrence of acute pancreatitis within a sample of adults from northern China. METHODOLOGY: A total of 123,214 participants from the Kailuan Group were incorporated into this prospective study. The subjects were categorized into quartiles on the basis of their initial levels of triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C). On the basis of BMI classification, the individuals in the study were divided into three distinct groups: normal weight, overweight, and obese. The data were analyzed to explore the correlation between lipid profile and BMI with acute pancreatitis.

resultsOver a period of 12.59 ± 0.98 years, during the median follow-up duration, a total of 410 new patients with acute pancreatitis were recorded. The occurrence rate and total occurrence of acute pancreatitis demonstrated an upward trend in correlation with elevated levels of TG, TC, and BMI. Following adjustment for multiple variables, it was observed that individuals in the fourth quartile of TG and TC levels demonstrated the highest likelihood of developing acute pancreatitis. Furthermore, our analysis revealed that a proportion of 19.29% of the correlation between BMI and the likelihood of experiencing acute pancreatitis can be attributed to the influence of elevated TG levels, whereas 12.69% of the association was mediated by higher TC.

conclusionsWe found that hypertriglyceridemia, hypercholesterolemia, and obesity were risk factors for acute pancreatitis, especially in young and middle-aged men.TG and TC were the mediating factors between BMI and the risk of acute pancreatitis.

Indexed as

Body Mass IndexHypercholesterolemiaHypertriglyceridemiaPancreatitisAcute DiseaseAdultAgedChinaFemaleHumansMaleMiddle AgedObesityProspective StudiesRisk FactorsTriglyceridesTriglyceridesAcute pancreatitisBody mass indexHypercholesterolemiaHypertriglyceridemiaProspective cohort study

Identifiers

PMID38987445

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.