Evidence map›Paper›PMID 38992127›Full record

ReviewNature medicine2024

Precision public health in the era of genomics and big data.

Megan C Roberts, Kathryn E Holt, Guilherme Del Fiol, Andrea A Baccarelli, Caitlin G Allen

Abstract readReview
In one paragraph

Review in Nature medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  6. Review
  7. Article
  8. Review
  9. Heterogeneous associations of cumulative heat exposure with cognitive decline among older Japanese adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  10. Digital Dermatology.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
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  18. Article
  19. Advancing genomics for waterborne pathogen surveillance in Australia.The Lancet regional health. Western Pacific · 2026
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Megan C RobertsDivision of Pharmaceutical Outcomes and Policy, University of North Carolina Eshelman School of Pharmacy, Chapel Hill, NC, USA. Megan.roberts@unc.edu.ORCID 0000-0003-3434-2773
Kathryn E HoltDepartment of Infection Biology, London School of Hygiene & Tropical Medicine, London, UK.ORCID 0000-0003-3949-2471
Guilherme Del FiolBiomedical Informatics, School of Medicine, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0001-9954-6799
Andrea A BaccarelliDepartment of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Caitlin G AllenDepartment of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, SC, USA.

Funding

Extracellular vesicles in Environmental Epidemiology Studies of AgingR35ES031688 · NIEHS · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Andrea Baccarelli · 2021 to 2026
$4.6M
GARDE: Scalable Clinical Decision Support for Individualized Cancer Risk ManagementU24CA274582 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI GUILHERME DEL FIOL, Kensaku Kawamoto · 2023 to 2026
$3.3M
Transdisciplinary Conference for Future Leaders in Precision Public HealthR13CA261073 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Caitlin Gloeckner Allen, Megan C. Roberts · 2021 to 2026
$161k
NCI NIH HHS R13 CA261073NCI NIH HHS U24 CA274582NIEHS NIH HHS R35 ES031688U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) R13CA261073-02U.S. Department of Health & Human Services | NIH | National Institute of Environmental Health Sciences (NIEHS) R35ES031688
6 · The paper itself

Abstract

Precision public health (PPH) considers the interplay between genetics, lifestyle and the environment to improve disease prevention, diagnosis and treatment on a population level-thereby delivering the right interventions to the right populations at the right time. In this Review, we explore the concept of PPH as the next generation of public health. We discuss the historical context of using individual-level data in public health interventions and examine recent advancements in how data from human and pathogen genomics and social, behavioral and environmental research, as well as artificial intelligence, have transformed public health. Real-world examples of PPH are discussed, emphasizing how these approaches are becoming a mainstay in public health, as well as outstanding challenges in their development, implementation and sustainability. Data sciences, ethical, legal and social implications research, capacity building, equity research and implementation science will have a crucial role in realizing the potential for 'precision' to enhance traditional public health approaches.

Indexed as

Big DataGenomicsPrecision MedicinePublic HealthHumans

Identifiers

PMID38992127
PMCPMC12017803

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.