Evidence mapPaperPMID 38998996Full record

ReviewMolecules (Basel, Switzerland)2024

Morpholine, Piperazine, and Piperidine Derivatives as Antidiabetic Agents.

Darya Zolotareva, Alexey Zazybin, Anuar Dauletbakov, Yelizaveta Belyankova, Beatriz Giner Parache, Saniya Tursynbek, Tulegen Seilkhanov, Anel Kairullinova

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Heterocycles in Medicinal Chemistry II.Molecules (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Darya ZolotarevaSchool of Chemical Engineering, Kazakh-British Technical University, 59 Tole bi Str., Almaty 050000, Kazakhstan.ORCID 0000-0002-4809-2616
Alexey ZazybinSchool of Chemical Engineering, Kazakh-British Technical University, 59 Tole bi Str., Almaty 050000, Kazakhstan.
Anuar DauletbakovSchool of Chemical Engineering, Kazakh-British Technical University, 59 Tole bi Str., Almaty 050000, Kazakhstan.
Yelizaveta BelyankovaSchool of Chemical Engineering, Kazakh-British Technical University, 59 Tole bi Str., Almaty 050000, Kazakhstan.ORCID 0000-0002-7418-0564
Beatriz Giner ParacheFacultad de Ciencias de la Salud, Universidad San Jorge, 50830 Zaragoza, Spain.ORCID 0000-0001-8669-2789
Saniya TursynbekSchool of Chemical Engineering, Kazakh-British Technical University, 59 Tole bi Str., Almaty 050000, Kazakhstan.ORCID 0000-0002-0492-5276
Tulegen SeilkhanovLaboratory of Engineering Profile NMR Spectroscopy, Sh. Ualikhanov Kokshetau University, 76 Abay Str., Kokshetau 020000, Kazakhstan.ORCID 0000-0003-0079-4755
Anel KairullinovaSchool of Chemical Engineering, Kazakh-British Technical University, 59 Tole bi Str., Almaty 050000, Kazakhstan.

Funding

Ministry of Science and Higher Education of the Republic of Kazakhstan AP19578051 and AP19676539
6 · The paper itself

Abstract

Diabetes mellitus is a severe endocrine disease that affects more and more people every year. Modern medical chemistry sets itself the task of finding effective and safe drugs against diabetes. This review provides an overview of potential antidiabetic drugs based on three heterocyclic compounds, namely morpholine, piperazine, and piperidine. Studies have shown that compounds containing their moieties can be quite effective in vitro and in vivo for the treatment of diabetes and its consequences.

Indexed as

Hypoglycemic AgentsMorpholinesPiperazinePiperidinesAnimalsDiabetes MellitusHumansPiperazinesStructure-Activity RelationshipHypoglycemic AgentsmorpholineMorpholinesPiperazinePiperazinespiperidinePiperidinesantidiabetic drugsdiabetesmorpholinepiperazinepiperidine

Identifiers

PMID38998996
PMCPMC11243478

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.