Evidence map›Paper›PMID 38999750›Full record

ArticleNutrients2024

Regulations of Citrus Pectin Oligosaccharide on Cholesterol Metabolism: Insights from Integrative Analysis of Gut Microbiota and Metabolites.

Haijuan Hu, Peipei Zhang, Fengxia Liu, Siyi Pan

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Haijuan HuCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Peipei ZhangCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Fengxia LiuCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Siyi PanCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.

Funding

Beijing Postdoctoral Research Foundation No. 2022-ZZ-113China Agriculture Research System of MOF and MARA No. CARS-26-07BFundamental Research Funds for the Central Universities No. 2662020SPPY011Major Special Projects and Key R&D Projects in Hubei Province No. 2022BBA0030Major Special Projects and Key R&D Projects in Yunnan Province No. 202102AE090054
6 · The paper itself

Abstract

(1) Background: Recently, academic studies are demonstrating that the cholesterol-lowering effects of pectin oligosaccharides (POSs) are correlated to intestinal flora. However, the mechanisms of POS on cholesterol metabolisms are limited, and the observations of intestinal flora are lacking integrative analyses. (2) Aim and methods: To reveal the regulatory mechanisms of POS on cholesterol metabolism via an integrative analysis of the gut microbiota, the changes in gut microbiota structure and metabolite composition after POS addition were investigated using Illumina MiSeq sequencing and non-targeted metabolomics through in vitro gut microbiota fermentation. (3) Results: The composition of fecal gut flora was adjusted positively by POS. POS increased the abundances of the cholesterol-related bacterial groups

Indexed as

CholesterolFecesFermentationGastrointestinal MicrobiomeOligosaccharidesPectinsBacteriaBifidobacteriumCitrusFatty Acids, VolatileFemaleHumansMaleMetabolomicsPrebioticsCholesterolcitrus pectinFatty Acids, VolatileOligosaccharidesPectinsPrebioticscholesterol metabolismcitrus pectin oligosaccharidesgut microbiota and metabolites

Identifiers

PMID38999750
PMCPMC11243408

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.