Evidence map›Paper›PMID 38999840›Full record

ReviewNutrients2024

Importance of Gut Microbiota in Patients with Inflammatory Bowel Disease.

Natalia Ekstedt, Dominika Jamioł-Milc, Joanna Pieczyńska

Abstract readReview
In one paragraph

Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Therapeutic Potential of Kinkeliba (Molecules (Basel, Switzerland) · 2026
    Article
  4. Review
  5. JGH open : an open access journal of gastroenterology and hepatology · 2025
    Review
  6. Nutrients · 2025
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Frontiers in microbiology · 2025
    Article
  13. Article
  14. Review
  15. Review
  16. The expression of intestinal Cyp2c55 is regulated by the microbiota and inflammation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  17. Nutrients · 2024
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Natalia EkstedtDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland.
Dominika Jamioł-MilcDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland.ORCID 0000-0003-0203-1823
Joanna PieczyńskaDepartment of Food Science and Dietetics, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel diseases (IBDs), such as Crohn's disease (CD) and ulcerative colitis (UC), are chronic diseases of the digestive system with a multifactorial and not fully understood etiology. There is research suggesting that they may be initiated by genetic, immunological, and lifestyle factors. In turn, all of these factors play an important role in the modulation of intestinal microflora, and a significant proportion of IBD patients struggle with intestinal dysbiosis, which leads to the conclusion that intestinal microflora disorders may significantly increase the risk of developing IBD. Additionally, in IBD patients, Toll-like receptors (TLRs) produced by intestinal epithelial cells and dendritic cells treat intestinal bacterial antigens as pathogens, which causes a disruption of the immune response, resulting in the development of an inflammatory process. This may result in the occurrence of intestinal dysbiosis, which IBD patients are significantly vulnerable to. In this study, we reviewed scientific studies (in particular, systematic reviews with meta-analyses, being studies with the highest level of evidence) regarding the microflora of patients with IBD vs. the microflora in healthy people, and the use of various strains in IBD therapy.

Indexed as

DysbiosisGastrointestinal MicrobiomeInflammatory Bowel DiseasesColitis, UlcerativeCrohn DiseaseHumansProbioticsCrohn’s diseaseinflammatory bowel diseasesmicrobiotaprobiotic strainsprobiotic therapyulcerative colitis

Identifiers

PMID38999840
PMCPMC11242987

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.