Evidence map›Paper›PMID 38999948›Full record

ReviewInternational journal of molecular sciences2024

Hematopoietic Stem Cells and Their Niche in Bone Marrow.

Munju Kwon, Byoung Soo Kim, Sik Yoon, Sae-Ock Oh, Dongjun Lee

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Aryl hydrocarbon receptor activation alters emergency hematopoiesis during influenza A virus infection.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Article
  8. 3DACS biomaterials science & engineering · 2026
    Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
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  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Munju KwonDepartment of Convergence Medicine, School of Medicine, Pusan National University, Yangsan 50612, Republic of Korea.
Byoung Soo KimSchool of Biomedical Convergence Engineering, Pusan National University, Yangsan 50612, Republic of Korea.ORCID 0000-0002-6693-0003
Sik YoonDepartment of Anatomy, School of Medicine, Pusan National University, Yangsan 50612, Republic of Korea.ORCID 0000-0002-6449-0761
Sae-Ock OhDepartment of Anatomy, School of Medicine, Pusan National University, Yangsan 50612, Republic of Korea.
Dongjun LeeDepartment of Convergence Medicine, School of Medicine, Pusan National University, Yangsan 50612, Republic of Korea.ORCID 0000-0001-6828-401X

Funding

Basic Science Research Program through the National Research Foundation (NRF) of Korea 2022R1A5A2027161Basic Science Research Program through the National Research Foundation (NRF) of Korea RS-2023-00223764Basic Science Research Program through the National Research Foundation (NRF) of Korea RS-2024-00333287Korean Cell-Based Artificial Blood Project funded by the Korean government HX23C1692
6 · The paper itself

Abstract

Extensive research has explored the functional correlation between stem cells and progenitor cells, particularly in blood. Hematopoietic stem cells (HSCs) can self-renew and regenerate tissues within the bone marrow, while stromal cells regulate tissue function. Recent studies have validated the role of mammalian stem cells within specific environments, providing initial empirical proof of this functional phenomenon. The interaction between bone and blood has always been vital to the function of the human body. It was initially proposed that during evolution, mammalian stem cells formed a complex relationship with the surrounding microenvironment, known as the niche. Researchers are currently debating the significance of molecular-level data to identify individual stromal cell types due to incomplete stromal cell mapping. Obtaining these data can help determine the specific activities of HSCs in bone marrow. This review summarizes key topics from previous studies on HSCs and their environment, discussing current and developing concepts related to HSCs and their niche in the bone marrow.

Indexed as

Bone MarrowHematopoietic Stem CellsStem Cell NicheAnimalsBone Marrow CellsHumansbone marrow microenvironmenthematopoietic progenitor cellshematopoietic stem cellsniche

Identifiers

PMID38999948
PMCPMC11241602

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.