ArticleInternational journal of molecular sciences2024
Synthesis of 3,4-Disubstituted Maleimide Derivatives via Phosphine-Catalyzed Isomerization of α-Succinimide-Substituted Allenoates Cascade γ'-Addition with Aryl Imines.
Zhenzhen Gao, Xiaoming Zhou, Baoshen Nie, Hanchong Lu, Xiaotong Chen, Jiahui Wu, Xuekun Wang, Lei Li
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In one paragraphArticle in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
8 authors.
Zhenzhen GaoSchool of Pharmaceutical Sciences, State Key Laboratory for Macromolecule Drugs and Large-Scale Manufacturing, Liaocheng University, Liaocheng 252059, China.ORCID 0000-0003-4955-092X Xiaoming ZhouSchool of Pharmaceutical Sciences, State Key Laboratory for Macromolecule Drugs and Large-Scale Manufacturing, Liaocheng University, Liaocheng 252059, China.
Baoshen NieSchool of Pharmaceutical Sciences, State Key Laboratory for Macromolecule Drugs and Large-Scale Manufacturing, Liaocheng University, Liaocheng 252059, China.
Hanchong LuSchool of Pharmaceutical Sciences, State Key Laboratory for Macromolecule Drugs and Large-Scale Manufacturing, Liaocheng University, Liaocheng 252059, China.
Xiaotong ChenSchool of Pharmaceutical Sciences, State Key Laboratory for Macromolecule Drugs and Large-Scale Manufacturing, Liaocheng University, Liaocheng 252059, China.
Jiahui WuSchool of Pharmaceutical Sciences, State Key Laboratory for Macromolecule Drugs and Large-Scale Manufacturing, Liaocheng University, Liaocheng 252059, China.
Xuekun WangSchool of Pharmaceutical Sciences, State Key Laboratory for Macromolecule Drugs and Large-Scale Manufacturing, Liaocheng University, Liaocheng 252059, China.ORCID 0000-0002-1457-0050 Lei LiSchool of Pharmaceutical Sciences, State Key Laboratory for Macromolecule Drugs and Large-Scale Manufacturing, Liaocheng University, Liaocheng 252059, China.ORCID 0000-0002-9729-2278 Funding
Guangyue Young Scholar Innovation Team Foundation of Liaocheng University LCUGYTD2022-04Shandong Province Natural Science Foundation ZR2021MB110the National Natural Science Foundation of China No. 22101002the Special Construction Project Fund for Shandong Province Taishan Scholars nothe Support Plan on Science and Technology for Youth Innovation of Universities in Shandong Province 2022KJ111
6 · The paper itselfAbstract
3,4-disubstituted maleimides find wide applications in various pharmacologically active compounds. This study presents a highly effective approach for synthesizing derivatives of 3,4-disubstituted maleimides through the direct isomerization of α-succinimide-substituted allenoates, followed by a cascade γ'-addition and aryl imines using PR
Indexed as
IminesMaleimidesPhosphinesSuccinimidesCatalysisIsomerismMolecular StructureStereoisomerismIminesmaleimideMaleimidesphosphinePhosphinessuccinimideSuccinimides3,4-disubstituted maleimidesallenoatesisomerizationphosphine-catalyzedγ′-addition
Identifiers
PMID39000025
PMCPMC11241244
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