Evidence map›Paper›PMID 39000032›Full record

ReviewInternational journal of molecular sciences2024

The Significance of Genetically Determined Methylation and Folate Metabolism Disorders in the Pathogenesis of Coronary Artery Disease: A Target for New Therapies?

Agnieszka Pietruszyńska-Reszetarska, Robert Pietruszyński, Robert Irzmański

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Agnieszka Pietruszyńska-ReszetarskaDepartment of Internal Medicine, Rehabilitation and Physical Medicine, Medical University of Lodz, 90-645 Lodz, Poland.ORCID 0000-0001-9194-7870
Robert PietruszyńskiCardiology Outpatient Clinic, Military Medical Academy Memorial Teaching Hospital of the Medical University of Lodz-Central Veterans' Hospital, 90-549 Lodz, Poland.
Robert IrzmańskiDepartment of Internal Medicine, Rehabilitation and Physical Medicine, Medical University of Lodz, 90-645 Lodz, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methylation is a biochemical process involving the addition of a methyl group (-CH

Indexed as

Coronary Artery DiseaseFolic AcidMethylenetetrahydrofolate Reductase (NADPH2)AnimalsBiomarkersDNA MethylationHumansMethylationPolymorphism, GeneticBiomarkersFolic AcidMethylenetetrahydrofolate Reductase (NADPH2)MTHFR protein, human5-MTHFbiomarkercoronary artery diseasefolatemethylationpersonalized medicine

Identifiers

PMID39000032
PMCPMC11241586

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.