Evidence mapPaperPMID 39000280Full record

ArticleInternational journal of molecular sciences2024

Reprogramming of Energy Metabolism in Human

Xuewen Song, Lauren Pickel, Hoon-Ki Sung, James Scholey, York Pei

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. The Role of Mitochondria in Polycystic Kidney Disease.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. NRF2 Dysregulation and Therapeutic Insights Across Chronic Kidney Diseases.International journal of molecular sciences · 2025
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xuewen SongDivision of Nephrology, University Health Network, Toronto, ON M5G 2N2, Canada.ORCID 0009-0005-4130-4136
Lauren PickelTranslational Medicine Program, The Hospital for Sick Children, Toronto, ON M5G 1E8, Canada.ORCID 0000-0001-6025-0915
Hoon-Ki SungTranslational Medicine Program, The Hospital for Sick Children, Toronto, ON M5G 1E8, Canada.ORCID 0000-0001-6677-9385
James ScholeyDivision of Nephrology, University Health Network, Toronto, ON M5G 2N2, Canada.
York PeiDivision of Nephrology, University Health Network, Toronto, ON M5G 2N2, Canada.

Funding

CIHR MOP 67084
6 · The paper itself

Abstract

Multiple alterations of cellular metabolism have been documented in experimental studies of autosomal dominant polycystic kidney disease (ADPKD) and are thought to contribute to its pathogenesis. To elucidate the molecular pathways and transcriptional regulators associated with the metabolic changes of renal cysts in ADPKD, we compared global gene expression data from human

Indexed as

Energy MetabolismPolycystic Kidney, Autosomal DominantSystems BiologyGene Expression RegulationHumansMechanistic Target of Rapamycin Complex 1MitochondriaOxidative PhosphorylationTRPP Cation ChannelsMechanistic Target of Rapamycin Complex 1TRPP Cation ChannelsADPKDglobal gene profilingmetabolic reprogrammingrenal cysts

Identifiers

PMID39000280
PMCPMC11240917

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.