Evidence mapPaperPMID 39000349Full record

ArticleInternational journal of molecular sciences2024

Lipid Emulsions Inhibit Labetalol-Induced Vasodilation in the Isolated Rat Aorta.

Soohee Lee, Kyeong-Eon Park, Yeran Hwang, Sungil Bae, Seong-Ho Ok, Seung-Hyun Ahn, Gyujin Sim, Hyun-Jin Kim, Seunghyeon Park, Ju-Tae Sohn

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Soohee LeeDepartment of Anesthesiology and Pain Medicine, Gyeongsang National University Changwon Hospital, Changwon-si 51472, Gyeongsangnam-do, Republic of Korea.ORCID 0000-0002-6047-633X
Kyeong-Eon ParkDepartment of Anesthesiology and Pain Medicine, Gyeongsang National University College of Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Yeran HwangDepartment of Anesthesiology and Pain Medicine, Gyeongsang National University College of Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Sungil BaeDepartment of Anesthesiology and Pain Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Seong-Ho OkDepartment of Anesthesiology and Pain Medicine, Gyeongsang National University Changwon Hospital, Changwon-si 51472, Gyeongsangnam-do, Republic of Korea.ORCID 0000-0002-1292-7108
Seung-Hyun AhnInstitute of Medical Science, Gyeongsang National University, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Gyujin SimInstitute of Medical Science, Gyeongsang National University, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.ORCID 0000-0002-5966-0180
Hyun-Jin KimDivision of Applied Life Science (BK21 Four), Gyeonsang National University, Jinju-si 52828, Gyeongsangnam-do, Republic of Korea.
Seunghyeon ParkDepartment of Anesthesiology and Pain Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Ju-Tae SohnInstitute of Medical Science, Gyeongsang National University, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.ORCID 0000-0003-0102-5800

Funding

Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Education IRIS RS-2023-00238572biomedical research institute fund from the Gyeongsang National Uni-versity Hospital GNUHBRIF-2023-0004
6 · The paper itself

Abstract

Lipid emulsions are used as adjuvant drugs to alleviate intractable cardiovascular collapse induced by drug toxicity. We aimed to examine the effect of lipid emulsions on labetalol-induced vasodilation and the underlying mechanism in the isolated rat aorta. We studied the effects of endothelial denudation, N

Indexed as

AortaCyclic GMPEmulsionsLabetalolNitric Oxide Synthase Type IIIVasodilationAnimalsCalciumEndothelium, VascularHumansHuman Umbilical Vein Endothelial CellsLipidsMaleNG-Nitroarginine Methyl EsterPhosphorylationRatsCalciumCyclic GMPEmulsionsLabetalolLipidsNG-Nitroarginine Methyl EsterNitric Oxide Synthase Type IIIendothelial nitric oxidelabetalollipid emulsionnitric oxidevasodilation

Identifiers

PMID39000349
PMCPMC11241312

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.