Evidence mapPaperPMID 39000424Full record

ReviewInternational journal of molecular sciences2024

Generation and Accumulation of Various Advanced Glycation End-Products in Cardiomyocytes May Induce Cardiovascular Disease.

Takanobu Takata, Shinya Inoue, Togen Masauji, Katsuhito Miyazawa, Yoshiharu Motoo

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Dietary Advanced Glycation End Products and Cardiovascular-Kidney-Metabolic Complications.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Review
  2. Potential of Orally Administered Quercetin, Hesperidin, andInternational journal of molecular sciences · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. WormCNN-Assisted Establishment and Analysis of Glycation Stress Models inInternational journal of molecular sciences · 2024
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Takanobu TakataDivision of Molecular and Genetic Biology, Department of Life Science, Medical Research Institute, Kanazawa Medical University, Uchinada, Ishikawa 920-0293, Japan.ORCID 0000-0003-0514-8584
Shinya InoueDepartment of Urology, Kanazawa Medical University, Uchinada, Ishikawa 920-0293, Japan.ORCID 0000-0001-8639-6955
Togen MasaujiDepartment of Pharmacy, Kanazawa Medical University Hospital, Uchinada, Ishikawa 920-0293, Japan.
Katsuhito MiyazawaDepartment of Urology, Kanazawa Medical University, Uchinada, Ishikawa 920-0293, Japan.ORCID 0000-0002-0331-3753
Yoshiharu MotooDepartment of Internal Medicine, Fukui Saiseikai Hospital, Wadanaka, Fukui 918-8503, Japan.

Funding

Japan Society for the Promotion of Science JP21K11607Japan Society for the Promotion of Science JP22K16798Japan Society for the Promotion of Science JP24K14802
6 · The paper itself

Abstract

Cardiomyocyte dysfunction and cardiovascular diseases (CVDs) can be classified as ischemic or non-ischemic. We consider the induction of cardiac tissue dysfunction by intracellular advanced glycation end-products (AGEs) in cardiomyocytes as a novel type of non-ischemic CVD. Various types of AGEs can be generated from saccharides (glucose and fructose) and their intermediate/non-enzymatic reaction byproducts. Recently, certain types of AGEs (

Indexed as

Cardiovascular DiseasesGlycation End Products, AdvancedMyocytes, CardiacAnimalsHumansMiceGlycation End Products, Advancedadvanced glycation end-products (AGEs)AGE patterncarbonyl trapcardiovascular diseaseF-actin–tropomyosin filamentglyoxalase-1 (GLO-1)massnatural productsryanodine receptor 2 (RyR2)traditional medicines

Identifiers

PMID39000424
PMCPMC11242264

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.