Evidence map›Paper›PMID 39000600›Full record

ArticleInternational journal of molecular sciences2024

Metformin Prevents Tumor Cell Growth and Invasion of Human Hormone Receptor-Positive Breast Cancer (HR+ BC) Cells via

Christine Song, Dawa Jung, Ayse Tuba Kendi, Jin Kyung Rho, Eun-Joo Kim, Ian Horn, Geoffry L Curran, Sujala Ghattamaneni, Ji Yeon Shim, Pil Soo Kang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Christine SongDivision of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Dawa JungDivision of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Ayse Tuba KendiDivision of Radiology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0003-3892-4754
Jin Kyung RhoDepartment of Convergence Medicine, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea.
Eun-Joo KimDepartment of Molecular Biology, Dankook University, Cheonan 31116, Chungcheongnam, Republic of Korea.
Ian HornDivision of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Geoffry L CurranDivision of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Sujala GhattamaneniDivision of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Ji Yeon ShimCollege of Nursing, Dankook University, Cheonan 31116, Chungcheongnam, Republic of Korea.
Pil Soo KangU&Hang Clinic, Asan 31514, Chungcheongnam, Republic of Korea.
Daehun KangDivision of Radiology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0003-3792-3303
Jay B ThakkarDivision of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Sannidhi DewanDivision of Radiology, Mayo Clinic, Rochester, MN 55905, USA.
Val J LoweDivision of Radiology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-5612-1667
Seung Baek LeeDivision of Radiology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-4754-4481

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Women with type 2 diabetes (T2D) have a higher risk of being diagnosed with breast cancer and have worse survival than non-diabetic women if they do develop breast cancer. However, more research is needed to elucidate the biological underpinnings of these relationships. Here, we found that forkhead box A1 (

Indexed as

Breast NeoplasmsCell ProliferationHepatocyte Nuclear Factor 3-alphaMetforminCell Line, TumorFemaleGene Expression Regulation, NeoplasticHumansMCF-7 CellsNeoplasm InvasivenessReceptors, EstrogenReceptors, ProgesteroneFOXA1 protein, humanHepatocyte Nuclear Factor 3-alphaMetforminReceptors, EstrogenReceptors, Progesteroneforkhead box A1 (FOXA1)hormone-receptor-positive (HR+) breast cancer (BC)metastasismetformintumor proliferationtype 2 diabetes (T2D)

Identifiers

PMID39000600
PMCPMC11242876

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.