ArticleDiagnostics (Basel, Switzerland)2024
The Role of Magnetic Resonance Imaging in Risk Stratification of Patients with Acute Myocarditis.
Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Article
- Recurrent Myocarditis in Young Adults: Identifying High-Risk Phenotypes and the Protective Effect of Adequate Colchicine Therapy.Medicina (Kaunas, Lithuania) · 2026Observational
- Article
- Cardiac Magnetic Resonance in Heart Failure: Diagnostic and Prognostic Assessments.Journal of cardiovascular development and disease · 2025Review
- Prevalence of Myocardial Infarction With Obstructive and Non-Obstructive Coronary Arteries in a Middle-Aged Population With Chronic Airflow Limitation: A Cross-Sectional Study.International journal of chronic obstructive pulmonary disease · 2025Article
- Reproducibility of late gadolinium enhancement quantification techniques in ischemic and non-ischemic heart diseases (ReLate study).Frontiers in cardiovascular medicine · 2025Article
- Computer-Assisted Algorithm for Quantification of Fibrosis by Native Cardiac CT: A Pilot Study.Journal of clinical medicine · 2024Article
- Cardiac magnetic resonance parameters associated with myocarditis in patients treated with immunotherapy: a scoping review.Archivos peruanos de cardiologia y cirugia cardiovascularReview
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiac magnetic resonance (cMRI) is often used to diagnose acute myocarditis (AM). It is also performed after 6 months to monitor myocardial involvement. However, the clinical and predictive relevance of the 6-month cMRI is uncertain.
objectiveWe used cMRI to assess the morphology and heart function of patients with AM, the correlation between left ventricular remodeling and biomarkers of heart dysfunction and myocardial fibrosis, and the involvement of myocardial fibrosis initially and 6 months after the acute episode. MATERIALS AND
methodsWe conducted a prospective study of 90 patients with the clinical suspicion of AM, where cMRI was performed within the first week after symptom onset and repeated after 6 months.
resultsNon-ischemic late gadolinium enhancement (LGE) was present in 88 (97.7%) patients and mainly involved the septum and inferior wall. cMRI at 6 months was associated with significantly reduced abnormalities of segmental kinetics (
conclusionsLGE, myocardial edema, and prolonged native T1 were predictors of MACEs. LGE does not necessarily mean constituted fibrosis in the presence of edema and may disappear over time. LGE without edema could represent fibrosis, whereas the persistence of edema represents active inflammation and could be associated with the residual chance of complete recovery. cMRI should be performed in all patients with AM at 6 months to evaluate progress and prognosis.
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