Evidence map›Paper›PMID 39001321›Full record

ReviewDiagnostics (Basel, Switzerland)2024

Technological Advances in SPECT and SPECT/CT Imaging.

Yassine Bouchareb, Afrah AlSaadi, Jawa Zabah, Anjali Jain, Aziza Al-Jabri, Peter Phiri, Jian Qing Shi, Gayathri Delanerolle, Srinivasa Rao Sirasanagandla

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. SPECT/CT Scan Images to Evaluate COVID-19 Pulmonary Complications: A Systematic Review.International journal of environmental research and public health · 2025
    Pooled it
  2. Review
  3. Review
  4. Optimisation of Q.Clear (BSREM) Reconstruction Parameters forBioengineering (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Quantification in bone SPECT/CT.Frontiers in nuclear medicine · 2026
    Review
  13. Review
  14. Review
  15. Article
  16. [Research progress on predicting radiation pneumonia based on four-dimensional computed tomography ventilation imaging in lung cancer radiotherapy].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yassine BoucharebDepartment of Radiology & Molecular Imaging, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat 123, Oman.ORCID 0000-0001-8819-9736
Afrah AlSaadiDepartment of Radiology & Molecular Imaging, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat 123, Oman.ORCID 0009-0009-9551-9836
Jawa ZabahDepartment of Radiology & Molecular Imaging, Sultan Qaboos University Hospital, Muscat 123, Oman.
Anjali JainSultan Qaboos Comprehensive Cancer Care and Research Centre, Department of Radiology, Muscat 123, Oman.
Aziza Al-JabriDepartment of Radiology & Molecular Imaging, Sultan Qaboos University Hospital, Muscat 123, Oman.
Peter PhiriSouthern Health NHS Foundation Trust, Southampton SO40 2RZ, UK.ORCID 0000-0001-9950-3254
Jian Qing ShiSouthern Health NHS Foundation Trust, Southampton SO40 2RZ, UK.
Gayathri DelanerolleSouthern Health NHS Foundation Trust, Southampton SO40 2RZ, UK.ORCID 0000-0002-9628-9245
Srinivasa Rao SirasanagandlaDepartment of Human & Clinical Anatomy, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat 123, Oman.ORCID 0000-0002-7261-1666

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single photon emission tomography/computed tomography (SPECT/CT) is a mature imaging technology with a dynamic role in the diagnosis and monitoring of a wide array of diseases. This paper reviews the technological advances, clinical impact, and future directions of SPECT and SPECT/CT imaging. The focus of this review is on signal amplifier devices, detector materials, camera head and collimator designs, image reconstruction techniques, and quantitative methods. Bulky photomultiplier tubes (PMTs) are being replaced by position-sensitive PMTs (PSPMTs), avalanche photodiodes (APDs), and silicon PMs to achieve higher detection efficiency and improved energy resolution and spatial resolution. Most recently, new SPECT cameras have been designed for cardiac imaging. The new design involves using specialised collimators in conjunction with conventional sodium iodide detectors (NaI(Tl)) or an L-shaped camera head, which utilises semiconductor detector materials such as CdZnTe (CZT: cadmium-zinc-telluride). The clinical benefits of the new design include shorter scanning times, improved image quality, enhanced patient comfort, reduced claustrophobic effects, and decreased overall size, particularly in specialised clinical centres. These noticeable improvements are also attributed to the implementation of resolution-recovery iterative reconstructions. Immense efforts have been made to establish SPECT and SPECT/CT imaging as quantitative tools by incorporating camera-specific modelling. Moreover, this review includes clinical examples in oncology, neurology, cardiology, musculoskeletal, and infection, demonstrating the impact of these advancements on clinical practice in radiology and molecular imaging departments.

Indexed as

artificial intelligencecollimator designreconstruction algorithmssolid-state detectorsSPECTSPECT/CT

Identifiers

PMID39001321
PMCPMC11241697

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.