Evidence map›Paper›PMID 39003275›Full record

ReviewNPJ biofilms and microbiomes2024

Recent advances in the pathogenesis and prevention strategies of dental calculus.

Yu Wei, Gao-Peng Dang, Zhao-Yang Ren, Mei-Chen Wan, Chen-Yu Wang, Hong-Bo Li, Tong Zhang, Franklin R Tay, Li-Na Niu

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in NPJ biofilms and microbiomes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06857474 (The Effect of Bristle Brush, Rubber Cup, and Air Polishing on Tooth Surface Roughness of Scaled Teeth), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06857474 nacompletednot on this mapstarted 2025, after this paper: background citation

The Effect of Bristle Brush, Rubber Cup, and Air Polishing on Tooth Surface Roughness of Scaled Teeth: A Randomized Controlled Trial Study Using Scanning Electron Microscope: Randomized Controlled Trial

TypeinterventionalSponsorKhyber Medical University PeshawarRan2025 to 2025Enrolled56ConditionsPeriodontal Diseases, Tooth Abrasion, Dental PlaqueArmsBristle Brush Polishing, Rubber Cup Polishing, Air Polishing, Ultrasonic Scaling
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yu Wei *State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Gao-Peng Dang *State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi, China.ORCID http://orcid.org/0000-0003-4741-2662
Zhao-Yang Ren *State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Mei-Chen WanState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Chen-Yu WangState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Hong-Bo LiDepartment of Stomatology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Tong ZhangDepartment of Stomatology, the First Medical Center, Chinese PLA General Hospital, Beijing, China.
Franklin R TayThe Dental College of Georgia, Augusta University, Augusta, GA, USA.
Li-Na NiuState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Key Laboratory of Stomatology, Department of Prosthodontics, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi, China. niulina831013@126.com.ORCID http://orcid.org/0000-0002-6653-0819

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82170798National Natural Science Foundation of China (National Science Foundation of China) 82170978
6 · The paper itself

Abstract

Dental calculus severely affects the oral health of humans and animal pets. Calculus deposition affects the gingival appearance and causes inflammation. Failure to remove dental calculus from the dentition results in oral diseases such as periodontitis. Apart from adversely affecting oral health, some systemic diseases are closely related to dental calculus deposition. Hence, identifying the mechanisms of dental calculus formation helps protect oral and systemic health. A plethora of biological and physicochemical factors contribute to the physiological equilibrium in the oral cavity. Bacteria are an important part of the equation. Calculus formation commences when the bacterial equilibrium is broken. Bacteria accumulate locally and form biofilms on the tooth surface. The bacteria promote increases in local calcium and phosphorus concentrations, which triggers biomineralization and the development of dental calculus. Current treatments only help to relieve the symptoms caused by calculus deposition. These symptoms are prone to relapse if calculus removal is not under control. There is a need for a treatment regime that combines short-term and long-term goals in addressing calculus formation. The present review introduces the mechanisms of dental calculus formation, influencing factors, and the relationship between dental calculus and several systemic diseases. This is followed by the presentation of a conceptual solution for improving existing treatment strategies and minimizing recurrence.

Indexed as

BiofilmsDental CalculusAnimalsBacteriaCalciumHumansMouthOral HealthPhosphorusCalciumPhosphorus

Identifiers

PMID39003275
PMCPMC11246453

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.