ArticleEnvironmental health : a global access science source2024
Association between brominated flame retardants (PBDEs and PBB153) exposure and hypertension in U.S. adults: results from NHANES 2005-2016.
Article in Environmental health : a global access science source, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- Associations Between Polybrominated Diphenyl Ethers and Biological Aging in NHANES 2005-2010 and 2015-2016.GeoHealth · 2026Article
- Association between exposure to brominated flame retardants (BFRs) and blood lipid profiles in American adults: a cross-sectional study.Lipids in health and disease · 2025Article
- Associations between exposure to brominated flame retardants and hyperlipidemia risk in U.S. Adults.BMC public health · 2025Article
- Combined exposure to mixed brominated flame retardants on obstructive sleep apnea syndrome in US adults.BMC public health · 2025Article
- Sex-specific associations between brominated flame retardants exposure and phenotypic age acceleration in NHANES 2005-2010.Frontiers in public health · 2025Article
- Article
- Inflammation mediation of the association between brominated flame retardants and psoriasis among U.S. adults.Frontiers in public health · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundBrominated Flame Retardants (BFRs) have attracted widespread concern due to their environmental persistence and potential toxicity. This study aims to examine the association between BFRs exposure and hypertension.
methodsWe used data from the National Health and Nutrition Examination Survey (NHANES) spanning 2005 to 2016 for the cross-sectional analysis. To evaluate the individual and combined impacts of BFRs exposure on hypertension, we utilized multivariate models, including generalized additive models, weighted quantile sum (WQS) regression, and Bayesian kernel machine regression (BKMR) models.
results9882 individuals (48% male) aged ≥ 20 were included in the final analysis, of whom 4114 had hypertension. After controlling for potential covariates, higher serum concentrations of PBDE100 (OR: 1.26; 95% CI: 1.01, 1.57) and PBDE153 (OR: 1.50; 95% CI: 1.18, 1.88) were significantly associated with hypertension. A nonlinear relationship between PBDE28 and hypertension was observed (P = 0.03). Moreover, BFRs mixture were positively associated with the prevalence of hypertension in both the WQS (β:1.09; 95% CI: 1.02, 1.17; P = 0.02) and BKMR models.
conclusionOur study suggested that BFRs exposure is positively associated with hypertension in the general population. To confirm this association and elucidate the mechanisms, further research is required.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.