Evidence map›Paper›PMID 39003493›Full record

ArticleBMC cardiovascular disorders2024

Uric acid to albumin ratio as a novel predictor for coronary slow flow phenomenon in patients with chronic coronary syndrome and non-obstructive coronary arteries.

Xiao-Jiao Zhang, Ai-Jie Hou, Bo Luan, Cheng-Fu Wang, Jia-Jin Li

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Article in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Xiao-Jiao ZhangDepartment of Cardiology, The People's Hospital of Liaoning Province, The People's Hospital of China Medical University, Shenyang, China.
Ai-Jie HouDepartment of Cardiology, The People's Hospital of Liaoning Province, The People's Hospital of China Medical University, Shenyang, China.
Bo LuanDepartment of Cardiology, The People's Hospital of Liaoning Province, The People's Hospital of China Medical University, Shenyang, China.
Cheng-Fu WangDepartment of Cardiology, The People's Hospital of Liaoning Province, The People's Hospital of China Medical University, Shenyang, China.
Jia-Jin LiDepartment of Cardiology, The People's Hospital of Liaoning Province, The People's Hospital of China Medical University, Shenyang, China. drlijiajin@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe plasma uric acid to albumin ratio (UAR) is considered as a novel indicator for Inflammation. However, the association between UAR and coronary slow flow phenomenon (CSFP) remains unclear.

methodsA total of 1328 individuals with chronic coronary syndrome (CCS) receiving coronary angiography (CAG) and found no obvious obstructive stenosis (< 40%) were included in this study. 79 individuals developed CSFP and were divided into CSFP group. The 1:2 age-matched patients with normal coronary blood flow were allocated to the control group (n = 158). The clinical characteristics, laboratory parameters including uric acid, albumin ratio, UAR and the angiographic characteristics were compared between the two groups.

resultsPatients with CSFP had a higher level of uric acid (392.3 ± 85.3 vs. 273.8 ± 71.5, P < 0.001), UAR (10.7 ± 2.2 vs. 7.2 ± 1.9, P < 0.001), but a lower level of plasma albumin (36.9 ± 4.2 vs. 38.5 ± 3.6, P = 0.003). Moreover, UAR increased as the numbers of vessels involved in CSFP increased. The logistic regression analysis demonstrated that UAR was independent predictors for CSFP. The Receiver operating characteristic (ROC) curve analysis showed that when UAR was more than 7.9, the AUC was 0.883 (95% CI: 0.840-0.927, p < 0.001), with the sensitivity and specificity were 78.2% and 88.2% respectively.

conclusionCombined uric acid with plasma albumin, UAR could serve as an independent predictor for CSFP.

Indexed as

BiomarkersCoronary AngiographyCoronary CirculationNo-Reflow PhenomenonPredictive Value of TestsSerum Albumin, HumanUric AcidAgedCase-Control StudiesChronic DiseaseCoronary Artery DiseaseCoronary VesselsFemaleHumansMaleMiddle AgedALB protein, humanBiomarkersSerum Albumin, HumanUric AcidChronic coronary syndromeCoronary artery diseaseCoronary slow flow phenomenonPredictorsUric acid to albumin ratio

Identifiers

PMID39003493
PMCPMC11245809

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.