Evidence map›Paper›PMID 39004663›Full record

ReviewHuman cell2024

The function of long non-coding RNA IFNG-AS1 in autoimmune diseases.

Jiale Zhao, Yibei Gui, Wei Wu, Xueqing Li, Lijun Wang, Hailin Wang, Yiyang Luo, Gang Zhou, Chengfu Yuan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Human cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiale ZhaoHubei Key Laboratory of Tumor Microenvironment and Immunotherapy, China Three Gorges University, Yichang, 443002, China.
Yibei GuiHubei Key Laboratory of Tumor Microenvironment and Immunotherapy, China Three Gorges University, Yichang, 443002, China.
Wei WuHubei Key Laboratory of Tumor Microenvironment and Immunotherapy, China Three Gorges University, Yichang, 443002, China.
Xueqing LiCollege of Medicine and Health Science, China Three Gorges University, Yichang, 443002, China.
Lijun WangHubei Key Laboratory of Tumor Microenvironment and Immunotherapy, China Three Gorges University, Yichang, 443002, China.
Hailin WangHubei Key Laboratory of Tumor Microenvironment and Immunotherapy, China Three Gorges University, Yichang, 443002, China.
Yiyang LuoCollege of Medicine and Health Science, China Three Gorges University, Yichang, 443002, China.
Gang ZhouCollege of Traditional Chinese Medicine, China Three Gorges University, Yichang, 443002, China. 13661880@qq.com.
Chengfu YuanHubei Key Laboratory of Tumor Microenvironment and Immunotherapy, China Three Gorges University, Yichang, 443002, China. yuancf46@ctgu.edu.cn.ORCID http://orcid.org/0000-0002-1894-0960

Funding

innovational group project of Hubei Province Natural Science Foundation in China No. 2021CFA015National Natural Science Foundation of China No. 81773959National Natural Science Foundation of China No. 81974528National Natural Science Foundation of China No. 82174035National Natural Science Foundation of China No. 82374107Open Foundation for Tumor Microenvironment and Immunotherapy Key Laboratory of Hubei province in China No. 2023KZL01
6 · The paper itself

Abstract

The prevalence of autoimmune diseases ranks as the third most common disease category globally, following cancer and heart disease. Numerous studies indicate that long non-coding RNA (lncRNA) plays a pivotal role in regulating human growth, development, and the pathogenesis of various diseases. It is more than 200 nucleotides in length and is mostly involve in the regulation of gene expression. Furthermore, lncRNAs are crucial in the development and activation of immune cells, with an expanding body of research exploring their association with autoimmune disorders in humans. LncRNA Ifng antisense RNA 1 (IFNG-AS1), a key regulatory factor in the immune system, also named NeST or TMEVPG1, is proximally located to IFNG and participates in the regulation of it. The dysregulation of IFNG-AS1 is implicated in the pathogenesis of several autoimmune diseases. This study examines the role and mechanism of IFNG-AS1 in various autoimmune diseases and considers its potential as a therapeutic target.

Indexed as

Autoimmune DiseasesInterferon-gammaRNA, Long NoncodingGene ExpressionGene Expression RegulationHumansMolecular Targeted TherapyInterferon-gammaRNA, Long NoncodingAutoimmune diseasesIFNG-AS1IFN-γImmune systemLncRNA

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.