Evidence map›Paper›PMID 39005344›Full record

ArticlebioRxiv : the preprint server for biology2024

Phospholipase Cγ regulates lacrimal gland branching by competing with PI3K in phosphoinositide metabolism.

Qian Wang, Chenqi Tao, Yihua Wu, Karen E Anderson, Abdul Hannan, Chyuan-Sheng Lin, Phillip Hawkins, Len Stephens, Xin Zhang

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Chenqi Tao
Yihua Wu
Karen E Anderson
Abdul Hannan
Chyuan-Sheng Lin
Phillip Hawkins
Len Stephens
Xin Zhang

Funding

Signaling networks and transcriptional programs in lens vesicle formationK99EY032171 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WANG, QIAN · 2022 to 2023
$237k
NEI NIH HHS K99 EY032171
6 · The paper itself

Abstract

Although the regulation of branching morphogenesis by spatially distributed cues is well established, the role of intracellular signaling in determining the branching pattern remains poorly understood. In this study, we investigated the regulation and function of phospholipase C gamma (PLCγ) in Fibroblast Growth Factor (FGF) signaling in lacrimal gland development. We showed that deletion of

Identifiers

PMID39005344
PMCPMC11244885

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.