ArticleAmerican journal of preventive cardiology2024
Epicardial fat modifies the relationship between coronary calcium score and all-cause mortality: The St. Francis Heart Study.
Article in American journal of preventive cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Prognostic value of epicardial and pericardial adipose tissue in patients with chronic heart failure.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2026Article
- Critique on "Epicardial Fat Thickness as a Marker of Coronary Artery Disease in Diabetics: A Single Center Study".Clinical cardiology · 2026Article
- Association between region-specific epicardial adipose tissue and CT-derived fractional flow reserve-defined myocardial ischemia: a retrospective coronary CTA study stratified by hypertension and type 2 diabetes mellitus.Frontiers in medicine · 2026Article
- Epicardial fat density obtained with computed tomography imaging - more important than volume?Cardiovascular diabetology · 2024Review
- Lipid Accumulation Product Is Predictive of Cardiovascular Hospitalizations among Patients with Stable Ischemic Heart Disease: Long-Term Follow-Up of the LAERTES Study.Journal of cardiovascular development and disease · 2024Article
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Authors and funding
8 authors.
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Abstract
Objective: Epicardial fat is associated with cardiovascular risk factors and adverse outcomes. However, it is not clear if epicardial fat remains to be a mortality risk when coronary calcium score (CAC) is taken into account. Methods: We studied the 1005 participants from the St. Francis Heart Study who were apparently healthy with CAC scores at 80th percentile or higher for age and gender, randomly assigned to placebo or statin therapy. At baseline, lipid profiles and non-contrast CT images were obtained where the epicardial fat volume was analyzed. Likelihood ratio testing was used to assess the additional prognostic value of epicardial fat to CAC for the risk of all-cause mortality. Results: Increased epicardial fat volume was associated with higher CAC. For each unit increase in lnCAC, the average epicardial fat volume increased by 3.34 mL/m Conclusion: Increased epicardial fat volume is associated with increased all-cause mortality risk. In addition, it portends incremental prognostic value to CAC score in mortality prediction.
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