Evidence map›Paper›PMID 39006361›Full record

Trial reportFrontiers in endocrinology2024

Maternal vitamin A and D status in second and third trimester of pregnancy and bone mineral content in offspring at nine years of age.

Astrid Kamilla Stunes, Mats Peder Mosti, Miriam Katarina Gustafsson, Torunn Børsting, Per Medbøe Thorsby, Signe Nilssen Stafne, Unni Syversen

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Astrid Kamilla StunesDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
Mats Peder MostiDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
Miriam Katarina GustafssonDepartment of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
Torunn BørstingCenter for Oral Health Services and Research, Mid-Norway (TkMidt), Trondheim, Norway.
Per Medbøe ThorsbyHormone Laboratory, Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway.
Signe Nilssen StafneDepartment of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
Unni SyversenDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Maternal nutritional and vitamin status during pregnancy may have long-term effects on offspring health and disease. The aim of this study was to examine the associations between maternal vitamin A and D status in pregnancy and offspring bone mineral content (BMC) at nine years of age. Methods: This is a Results: A total of 119 mother and child pairs were included in the analyses. Vitamin A insufficiency (retinol Conclusion: We observed a high prevalence of vitamin A insufficiency and vitamin D deficiency during pregnancy. A negative association between mid-pregnancy vitamin A status and spine BMC was observed in boys, but not girls, while no associations were found between maternal vitamin D status and child BMC. The implications of optimal vitamin A and D status in pregnancy for offspring bone health, remains a subject for further investigations.

Indexed as

Bone DensityPregnancy Trimester, SecondPregnancy Trimester, ThirdVitamin AVitamin DAdultChildFemaleHumansMaleMaternal Nutritional Physiological PhenomenaNorwayPregnancyPrenatal Exposure Delayed EffectsVitamin A DeficiencyVitamin D DeficiencyVitamin AVitamin D1,25(OH)2D25(OH)Doffspring bone masspregnancyretinolvitamin Avitamin D

Identifiers

PMID39006361
PMCPMC11239386

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.