Evidence mapPaperPMID 39010840Full record

ReviewAmerican journal of physiology. Cell physiology2024

Implications of pregnancy on cardiometabolic disease risk: preeclampsia and gestational diabetes.

Mona Elgazzaz, Padmashree C Woodham, James Maher, Jessica L Faulkner

Abstract readReview
In one paragraph

Review in American journal of physiology. Cell physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Emerging Role of Leptin in Vascular and Placental Dysfunction in Preeclampsia.Arteriosclerosis, thrombosis, and vascular biology · 2025
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mona ElgazzazDepartment of Physiology, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.
Padmashree C WoodhamDepartment of Obstetrics and Gynecology, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.
James MaherDepartment of Obstetrics and Gynecology, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.
Jessica L FaulknerDepartment of Physiology, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.ORCID 0000-0003-3362-412X

Funding

Regulation and role of leptin in preeclampsiaR01HL169576 · AUGUSTA UNIVERSITY · 2025 to 2025
$531k
HHS | National Institutes of Health (NIH) 1R01HL169576HHS | National Institutes of Health (NIH) 4R00HL146948NHLBI NIH HHS R00 HL146948NHLBI NIH HHS R01 HL169576
6 · The paper itself

Abstract

Cardiometabolic disorders, such as obesity, insulin resistance, and hypertension, prior to and within pregnancy are increasing in prevalence worldwide. Pregnancy-associated cardiometabolic disease poses a great risk to the short- and long-term well-being of the mother and offspring. Hypertensive pregnancy, notably preeclampsia, as well as gestational diabetes are the major diseases of pregnancy growing in prevalence as a result of growing cardiometabolic disease prevalence. The mechanisms whereby obesity, diabetes, and other comorbidities lead to preeclampsia and gestational diabetes are incompletely understood and continually evolving in the literature. In addition, novel therapeutic avenues are currently being explored in these patients to offset cardiometabolic-induced adverse pregnancy outcomes in preeclamptic and gestational diabetes pregnancies. In this review, we discuss the emerging pathophysiological mechanisms of preeclampsia and gestational diabetes in the context of cardiometabolic risk as well as the most recent preclinical and clinical updates in the pathogenesis and treatment of these conditions.

Indexed as

Diabetes, GestationalPre-EclampsiaAnimalsCardiometabolic Risk FactorsCardiovascular DiseasesFemaleHumansInsulin ResistanceObesityPregnancyRisk Factorsgestational diabetesmetabolismpreeclampsiapregnancy

Identifiers

PMID39010840
PMCPMC11427017

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.