ArticleBrain structure & function2024
Sex-related variability of white matter tracts in the whole HCP cohort.
Article in Brain structure & function, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Urological Malformations Identify the High-Burden Phenotype Among Children Hospitalized for Presumed Urinary Tract Infection: A Retrospective Cohort.Diagnostics (Basel, Switzerland) · 2026Article
- Sex-related Variability of White-Matter Tracts is Robust to Tractography Methodology.Research square · 2026Article
- Sex versus Gender Role Endorsement Associations With White Matter Microstructure in South African Adults: A Diffusion Tensor Imaging Study.Brain and behavior · 2026Article
- Study of sex differences in the whole brain white matter using diffusion MRI tractography and suprathreshold fiber cluster statistics.NeuroImage. Clinical · 2026Article
- White matter microstructural and macrostructural profiles during midlife reveal sex differences between men and women at different menopausal stages.Scientific reports · 2025Article
- Global and tract-specific differences between younger and older adults in DTI measures of white matter integrity.Frontiers in aging neuroscience · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Behavioral differences between men and women have been studied extensively, as have differences in brain anatomy. However, most studies have focused on differences in gray matter, while white matter has been much less studied. We conducted a comprehensive study of 77 deep white matter tracts to analyze their volumetric and microstructural variability between men and women in the full Human Connectome Project (HCP) cohort of 1065 healthy individuals aged 22-35 years. We found a significant difference in total brain volume between men and women (+ 12.6% in men), consistent with the literature. 16 tracts showed significant volumetric differences between men and women, one of which stood out due to a larger effect size: the corpus callosum genu, which was larger in women (+ 7.3% in women, p = 5.76 × 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.