Evidence map›Paper›PMID 39013367›Full record

Trial reportThe American journal of tropical medicine and hygiene2024

Neonatal Azithromycin Exposure and Childhood Growth: Long-Term Follow-Up of a Randomized Controlled Trial.

Mamadou Bountogo, Lucienne Ouermi, Clarisse Dah, Ali Sié, Boubacar Coulibaly, Alphonse Zakane, Thierry Ouedraogo, Mamadou Ouattara, Elodie Lebas, Ian Fetterman and 4 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of tropical medicine and hygiene, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mamadou BountogoCentre de Recherche en Sante de Nouna, Nouna, Burkina Faso.
Lucienne OuermiCentre de Recherche en Sante de Nouna, Nouna, Burkina Faso.
Clarisse DahCentre de Recherche en Sante de Nouna, Nouna, Burkina Faso.
Ali SiéCentre de Recherche en Sante de Nouna, Nouna, Burkina Faso.
Boubacar CoulibalyCentre de Recherche en Sante de Nouna, Nouna, Burkina Faso.
Alphonse ZakaneCentre de Recherche en Sante de Nouna, Nouna, Burkina Faso.
Thierry OuedraogoCentre de Recherche en Sante de Nouna, Nouna, Burkina Faso.
Mamadou OuattaraCentre de Recherche en Sante de Nouna, Nouna, Burkina Faso.
Elodie LebasFrancis I Proctor Foundation, University of California, San Francisco, California.
Ian FettermanFrancis I Proctor Foundation, University of California, San Francisco, California.
Aimée KimfuemaFrancis I Proctor Foundation, University of California, San Francisco, California.
Thuy DoanFrancis I Proctor Foundation, University of California, San Francisco, California.
Thomas M LietmanFrancis I Proctor Foundation, University of California, San Francisco, California.
Catherine E OldenburgFrancis I Proctor Foundation, University of California, San Francisco, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single-dose azithromycin is being considered by the WHO as an intervention for prevention of child mortality. However, concerns have emerged related to longer term unintended consequences of early life antibiotic use, particularly among infants. We conducted a long-term follow-up in a random sample of children who had been enrolled in a trial of neonatal azithromycin versus placebo for prevention of mortality to assess whether neonatal azithromycin exposure led to differences in child growth up to 4 years of age. We found no evidence of a difference in any anthropometric outcome among children who had received a single oral dose of azithromycin compared with placebo during the neonatal period. These results do not support long-term growth-promoting or deleterious effects of early life azithromycin exposure.

Indexed as

Anti-Bacterial AgentsAzithromycinChild DevelopmentChild MortalityChild, PreschoolFemaleFollow-Up StudiesHumansInfantInfant, NewbornMaleAnti-Bacterial AgentsAzithromycin

Identifiers

PMID39013367
PMCPMC11376181

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.