Evidence map›Paper›PMID 39019161›Full record

ArticleThe Journal of nutrition2024

The EAT-Lancet Diet Index Is Associated with Lower Obesity and Incidence of Type 2 Diabetes in the Multiethnic Cohort.

Rebecca Klapp, Julie Ann Laxamana, Yurii B Shvetsov, Song-Yi Park, Rieko Kanehara, Veronica Wendy Setiawan, Ina Danquah, Loïc Le Marchand, Gertraud Maskarinec

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In one paragraph

Article in The Journal of nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rebecca KlappPopulation Sciences in the Pacific, University of Hawaii Cancer Center, Honolulu, HI, United States.
Julie Ann LaxamanaPopulation Sciences in the Pacific, University of Hawaii Cancer Center, Honolulu, HI, United States.
Yurii B ShvetsovPopulation Sciences in the Pacific, University of Hawaii Cancer Center, Honolulu, HI, United States.
Song-Yi ParkPopulation Sciences in the Pacific, University of Hawaii Cancer Center, Honolulu, HI, United States.
Rieko KaneharaDivision of Epidemiology, National Cancer Center Japan, Tokyo, Japan.
Veronica Wendy SetiawanCenter for Genetic Epidemiology, University of Southern California, Los Angeles, CA, United States.
Ina DanquahCenter for Development Research, University of Bonn, Bonn, Germany.
Loïc Le MarchandPopulation Sciences in the Pacific, University of Hawaii Cancer Center, Honolulu, HI, United States.
Gertraud MaskarinecPopulation Sciences in the Pacific, University of Hawaii Cancer Center, Honolulu, HI, United States. Electronic address: gertraud@cc.hawaii.edu.

Funding

University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI Pallav Pokhrel · 1996 to 2026
$56.2M
Understanding Population Differences in Cancer: The MEC StudyU01CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2015 to 2025
$37.4M
Recruitment and Data CollectionP01CA168530 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI LE MARCHAND, LOIC · 2012 to 2016
$19.9M
Cancer Research Education, Advancement, Training and Empowerment (CREATE) in the PacificR25CA244073 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI Joseph Keawe'aimoku Kaholokula, LENORA WM LOO · 2020 to 2026
$1.9M
NCI NIH HHS P01 CA168530NCI NIH HHS P30 CA071789NCI NIH HHS R25 CA244073NCI NIH HHS U01 CA164973
6 · The paper itself

Abstract

backgroundThe EAT-Lancet Commission has developed dietary recommendations, named the EAT-Lancet diet, to promote healthy nutrition and sustainable food production worldwide.

objectivesWe developed an adapted score for the EAT-Lancet diet for participants of the Multiethnic Cohort (MEC) Study and its relation with incidence of obesity and type 2 diabetes (T2D).

methodsThe MEC includes 5 ethnic groups followed since 1993-1996. Anthropometric characteristics and dietary intake were assessed by questionnaire at cohort entry (Qx1) and 10 y later (Qx3). To create the EAT-Lancet index (range: 0-48 points), a 3-point scoring system for 16 food groups standardized to 2500 kcal/d was applied. T2D cases were identified through repeated self-reports and administrative data. In a prospective design, obesity at Qx3 and T2D incidence were evaluated using Cox regression to estimate hazard ratios (HR) with 95% confidence intervals (95% CI) while adjusting for relevant covariates.

resultsAmong 193,379 MEC participants, the overall mean of the EAT-Lancet index score was 25 ± 4 points and 46,140 new T2D cases were identified. Higher adjusted means were observed in females than males, in participants of Japanese American and Native Hawaiian ancestry, and in those with healthy weight than overweight or obese. Obesity was lower in cohort members with higher EAT-Lancet scores (HR: 0.76; 95% CI: 0.73, 0.79 for tertile 3 compared with 1). Although T2D incidence was 10% lower among participants in the highest (27-42 points) compared with the lowest (9-23 points) EAT-Lancet index tertile (HR: 0.90; 95% CI: 0.88, 0.92), the association was attenuated after BMI adjustment (HR: 0.97; 95% CI: 0.94, 0.99). This inverse association with T2D was restricted to African American and European American participants.

conclusionsThese findings support the hypothesis that adherence to the EAT-Lancet diet is related to a lower risk of obesity, which may be partially responsible for the small reduction in T2D incidence.

Indexed as

Diabetes Mellitus, Type 2DietObesityAgedCohort StudiesEthnicityFemaleHumansIncidenceMaleMiddle AgedProspective StudiesBMIdietary patternethnicityprospective studytype 2 diabetes

Identifiers

PMID39019161
PMCPMC11600087

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.