Evidence map›Paper›PMID 39020021›Full record

ReviewInflammation research : official journal of the European Histamine Research Society ... [et al.]2024

The emerging role of fibrin(ogen) in cardiovascular disease.

Hong Lan, Shengtao Zhao, Yuting Xiong, Xiang-Zhen Yan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Decoding the Heart Failure Peptidome.Circulation. Heart failure · 2026
    Article
  3. Article
  4. Article
  5. A dual-antibody sandwich immunoassay using upconversion nanoparticles and magnetic beads for fibrinogen detection.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hong LanShanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology & Department of Periodontology, Stomatological Hospital and Dental School, Tongji University, Yanchang Road 399, Shanghai, 200072, P. R. China.
Shengtao ZhaoShanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology & Department of Periodontology, Stomatological Hospital and Dental School, Tongji University, Yanchang Road 399, Shanghai, 200072, P. R. China.
Yuting XiongShanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology & Department of Periodontology, Stomatological Hospital and Dental School, Tongji University, Yanchang Road 399, Shanghai, 200072, P. R. China.
Xiang-Zhen YanShanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology & Department of Periodontology, Stomatological Hospital and Dental School, Tongji University, Yanchang Road 399, Shanghai, 200072, P. R. China. xiangzhenyan03@163.com.

Funding

National Natural Science Foundation of China No. NSFC 81700978Natural Science Foundation of Shanghai No. 22S11902800, 22ZR1467300Shanghai Municipal Health Commission's Clinical Research Project 202340064
6 · The paper itself

Abstract

objectiveA coagulation factor called fibrinogen is produced by the liver and is proteolyzed by thrombin to become fibrin. The latest studies have revealed that fibrin(ogen) palys an essential role in the regulation of cardiovascular disease. Understanding the relationship and mechanism between fibrin(ogen) and cardiovascular disease is of great significance for maintaining overall health. The objective of this review is to discuss the specific involvement and underlying mechanisms of fibrin(ogen) in cardiovascular disease.

methodsA review was conducted using the PubMed database to identify and analyze the emerging role of fibrinogen in cardiovascular disease.

resultsThe literature review revealed that fibrin(ogen) plays a pivotal role in maintaining cardiovascular disease and are involved in the pathogenesis of cardiovascular disease. Fibrin(ogen) mainly influence various pathophysiological processes, such as participating in thrombosis formation, stimulating the inflammatory response, and other molecular pathways.

conclusionThis review focuses on the involvement of fibrin(ogen) in cardiovascular disease, with a particular emphasis on the main functions and underlying mechanisms by which fibrin(ogen) influence the pathogenesis and progression of these conditions. This review underscores the potential of fibrin(ogen) as therapeutic targets in managing cardiovascular disease.

Indexed as

Cardiovascular DiseasesFibrinogenAnimalsHumansInflammationThrombosisFibrinogenCardiovascular diseaseCoagulationFibrinFibrinogen

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.