Evidence map›Paper›PMID 39020087›Full record

ArticleCell biochemistry and biophysics2024

Salidroside Reduced Ca

Hongjin Wang, Xianzhen Wang, Yanping Feng, Kewei Zhang, Maodongzhi Peng, Xiaowei Wu, Yi Li

Abstract read
PubMed Publisher
In one paragraph

Article in Cell biochemistry and biophysics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hongjin WangDepartment of Burn and Plastic Surgery, Qinghai University Affiliated Hospital, Xining, 810001, China.
Xianzhen WangDepartment of Burn and Plastic Surgery, Qinghai University Affiliated Hospital, Xining, 810001, China.
Yanping FengDepartment of Burn and Plastic Surgery, Qinghai University Affiliated Hospital, Xining, 810001, China.
Kewei ZhangDepartment of Burn and Plastic Surgery, Qinghai University Affiliated Hospital, Xining, 810001, China.
Maodongzhi PengDepartment of Burn and Plastic Surgery, Qinghai University Affiliated Hospital, Xining, 810001, China.
Xiaowei WuDepartment of Burn and Plastic Surgery, Qinghai University Affiliated Hospital, Xining, 810001, China.
Yi LiDepartment of Burn and Plastic Surgery, Qinghai University Affiliated Hospital, Xining, 810001, China. 19685400@qq.com.

Funding

Qinghai Provincial Central Guidance Fund for Local Science and Technology Development 2023ZY0212The Chinese Academy of Sciences Western Young Scholars Program; Young and Middle-aged Research Foundation of Affiliated Hospital of Qinghai University ASRF-2017-YB-06Young and middle-aged lifting project of Qinghai Science and Technology Association 2019QHSKXRCTJ03
6 · The paper itself

Abstract

To investigate vascular endothelium damage in rats exposed to hypoxic and cold and the effect of salidroside in protecting against this damage. A rat isolated aortic ring hypoxia/cold model was established to simulate exposure to hypoxic and cold. The levels of endothelial cell injury markers were measured by ELISA. TEM was performed to observe the ultrastructure of vascular ring endothelial cells. In vitro assays were performed to verify the effect of salidroside on endothelial cells. CCK-8 and flow cytometry were performed to analyze endothelial cell survival and apoptosis, respectively. Ca

Indexed as

ApoptosisCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Endothelial CellsGlucosidesNitric OxideNitric Oxide Synthase Type IIIPhenolsAnimalsCalmodulinCell HypoxiaCells, CulturedCell SurvivalCold TemperatureMaleMitochondriaCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2CalmodulinGlucosidesNitric OxideNitric Oxide Synthase Type IIIPhenolsReactive Oxygen SpeciesrhodiolosideAglyconesEndothelial celleNOS/NOHypoxia/hypothermiaSalidroside

Identifiers

PMID39020087

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.