ReviewFrontiers in nutrition2024
Digestible indispensable amino acid score (DIAAS): 10 years on.
Review in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Diet Quality, Food Processing, and Nutrient Adequacy in Vegan, Vegetarian, and Omnivorous Dietary Patterns: A Critical Narrative Review.Nutrients · 2026Review
- From Single Foods to Whole Diets: A Critical Framework for Protein Quality Assessment Accounting for Complementarity and Matrix Effects.Comprehensive reviews in food science and food safety · 2026Review
- Protein Paradox: Protein Quality Based on Amino Acids Composition is Poorly Associated with Health Outcomes.Current nutrition reports · 2026Review
- Development of the Vegan Protein Quality (VPQ) tool to derive smarter vegan meals with high protein quality.Scientific reports · 2026Article
- Food and Drug Administration Expert Panel on Infant Formula "Operation Stork Speed" June 2025: Part 1, Nutrient Considerations.Advances in nutrition (Bethesda, Md.) · 2026Review
- A Factorial Model of the Minimum Metabolic Demand for Protein and Indispensable Amino Acids in Young Adult Males: Implications for Current Recommendations.The Journal of nutrition · 2026Article
- The Correct Nutritional Intake in the Prevention and Treatment of Skin Lesions in Patients With Spinal Cord Injury.Journal of clinical medicine research · 2026Review
- Physicochemical Properties of Safflower (Foods (Basel, Switzerland) · 2026Article
- Article
- Eliminate the In Vivo Digestibility Requirement for Protein Content Claims in North America to Align Consumer Purchasing Behavior with Dietary Guidelines.Current developments in nutrition · 2026Article
- Beyond daily totals: meal-level digestible indispensable amino acid score reveals how food groups shape protein quality in vegan diets.Frontiers in nutrition · 2026Article
- A review for nutritional value ofFrontiers in veterinary science · 2026Review
- Review
- Evaluation of digestibility and digestible indispensable amino acid score (DIAAS) of barley and corn protein concentrates using a minipig model.European journal of nutrition · 2025Article
- Probiotic Sheep Milk: Physicochemical Properties of Fermented Milk and Viability of Bacteria Under Simulated Gastrointestinal Conditions.Nutrients · 2025Article
- Fast and easy edible protein production by nitrogen-supplemented koji fermentation.NPJ science of food · 2025Article
- Dietary protein intake and overall diet quality in adults with cystic fibrosis following elexacaftor/tezacaftor/ivacaftor therapy.The British journal of nutrition · 2025Observational
- Protein Intake and Protein Quality Patterns in New Zealand Vegan Diets: An Observational Analysis Using Dynamic Time Warping.Nutrients · 2025Observational
- Red Meat Amino Acids for Beginners: A Narrative Review.Nutrients · 2025Review
- The Impact of Plant-Based Proteins on Muscle Mass and Strength Performance: A Comprehensive Review.Current nutrition reports · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of the review is to revisit the findings of the 2011 Food and Agriculture Organization of the United Nations (FAO) Expert Consultation on Dietary Protein Quality Evaluation in Human Nutrition, and to report on progress on uptake of the findings. It is evident that since 2011 there has been a concerted research effort to enhance an understanding of the protein quality of foods. The validity of the growing pig ileal protein digestibility assay has been confirmed and numerous studies reported using the growing pig as a model to give true ileal amino acid digestibility values for foods as consumed by humans. This has allowed for the determination of digestible indispensable amino acid scores (DIAAS) for a range of foods. A new non-invasive true ileal amino acid digestibility assay in humans which can be applied in different physiological states, called the dual-isotope assay, has been developed and applied to determine the DIAAS values of foods. It is concluded that DIAAS is currently the most accurate score for routinely assessing the protein quality rating of single source proteins. In the future, the accuracy of DIAAS can be enhanced by improved information on: the ideal dietary amino acid balance including the ideal dispensable to indispensable amino acid ratio; dietary indispensable amino acid requirements; effects of processing on ileal amino acid digestibility and lysine bioavailability. There is a need to develop rapid, inexpensive
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.