Evidence mapPaperPMID 39027934Full record

SynthesisCirculation. Cardiovascular quality and outcomes2024

Role of Health Care Professionals in the Success of Blood Pressure Control Interventions in Patients With Hypertension: A Meta-Analysis.

Katherine T Mills, Samantha S O'Connell, Meng Pan, Katherine M Obst, Hua He, Jiang He

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Circulation. Cardiovascular quality and outcomes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Impact of patient care teams on blood pressure control in patients with hypertension: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Current hypertension epidemiology and contemporary approaches using the "Real-World Evidence Cycle" framework.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Review
  8. Article
  9. Global trends in hypertension prevalence, awareness, treatment, and control.Current opinion in nephrology and hypertension · 2026
    Review
  10. Regional disparities in blood pressure control after hypertension treatment initiation in Japan: a real-world data analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Can we better prevent cardiovascular disease? 'Stayin' healthy to stay alive'.International journal of cardiology. Cardiovascular risk and prevention · 2025
    Review
  16. Observational
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Katherine T MillsDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA (K.T.M., S.S.O., M.P., K.M.O., H.H., J.H.).ORCID 0000-0002-4278-5788
Samantha S O'ConnellDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA (K.T.M., S.S.O., M.P., K.M.O., H.H., J.H.).ORCID 0000-0001-6347-4623
Meng PanDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA (K.T.M., S.S.O., M.P., K.M.O., H.H., J.H.).ORCID 0000-0002-6734-0865
Katherine M ObstDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA (K.T.M., S.S.O., M.P., K.M.O., H.H., J.H.).
Hua HeDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA (K.T.M., S.S.O., M.P., K.M.O., H.H., J.H.).
Jiang HeDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA (K.T.M., S.S.O., M.P., K.M.O., H.H., J.H.).ORCID 0000-0002-8286-9652

Funding

Tulane COBRE for Clinical and Translational Research in Cardiometabolic DiseasesP20GM109036 · TULANE UNIVERSITY OF LOUISIANA · 2025 to 2025
$2.2M
Church Wellness Coordinator–Led Intervention to Improve Hypertension Control in CommunitiesR01MD018193 · UT SOUTHWESTERN MEDICAL CENTER · 2025 to 2025
$1.5M
Community Health Worker-Led Church-Based Intervention for Eliminating Cardiovascular Health Disparities in African AmericansUH3HL151309 · TULANE UNIVERSITY OF LOUISIANA · 2025 to 2025
$1.3M
Implementing and Scaling Up a Team-based Care Strategy for Hypertension Control in Colombia and JamaicaUH3HL152373 · UNIVERSITY OF THE WEST INDIES · 2025 to 2025
$707k
NHLBI NIH HHS R01 HL133790NHLBI NIH HHS UH3 HL151309NHLBI NIH HHS UH3 HL152373NIA NIH HHS R33 AG068481NIA NIH HHS R61 AG068481NIGMS NIH HHS P20 GM109036NIMHD NIH HHS R01 MD018193
6 · The paper itself

Abstract

backgroundGlobally, only 13.8% of patients with hypertension have their blood pressure (BP) controlled. Trials testing interventions to overcome barriers to BP control have produced mixed results. Type of health care professional delivering the intervention may play an important role in intervention success. The goal of this meta-analysis is to determine which health care professionals are most effective at delivering BP reduction interventions.

methodsWe searched Medline and Embase (until December 2023) for randomized controlled trials of interventions targeting barriers to hypertension control reporting who led intervention delivery. One hundred articles worldwide with 116 comparisons and 90 474 participants with hypertension were included. Trials were grouped by health care professional, and the effects of the intervention on systolic and diastolic BP were combined using random effects models and generalized estimating equations.

resultsPharmacist-led interventions , community health worker-led interventions, and health educator-led interventions resulted in the greatest systolic BP reductions of -7.3 (95% CI, -9.1 to -5.6), -7.1 (95% CI, -10.8 to -3.4), and -5.2 (95% CI, -7.8 to -2.6) mm Hg, respectively. Interventions led by multiple health care professionals, nurses, and physicians also resulted in significant systolic BP reductions of -4.2 (95% CI, -6.1 to -2.4), -3.0 (95% CI, -4.2 to -1.9), and -2.4 (95% CI, -3.4 to -1.5) mm Hg, respectively. Similarly, the greatest diastolic BP reductions were -3.9 (95% CI, -5.2 to -2.5) mm Hg for pharmacist-led and -3.7 (95% CI, -6.6 to -0.8) mm Hg for community health worker-led interventions. In pairwise comparisons, pharmacist were significantly more effective than multiple health care professionals, nurses, and physicians at delivering interventions.

conclusionsPharmacists and community health workers are most effective at leading BP intervention implementation and should be prioritized in future hypertension control efforts.

Indexed as

Antihypertensive AgentsBlood PressureHypertensionPharmacistsRandomized Controlled Trials as TopicAdultAgedCommunity Health WorkersFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedNurse's RolePatient Care TeamPhysician's RoleAntihypertensive Agentsblood pressurecardiovascular diseaseshealth personnelhypertensionrisk factors

Identifiers

PMID39027934
PMCPMC11338746

What Socratic holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.