Evidence map›Paper›PMID 39028361›Full record

ArticleJournal of neurology2024

Temporalis muscle thickness as a predictor of functional outcome after reperfusion therapies for acute ischemic stroke: a retrospective, cohort study.

Beatrice Ravera, Chiara Lombardi, Simone Bellavia, Irene Scala, Fabiana Cerulli, Eleonora Torchia, Sara Bortolani, Pier Andrea Rizzo, Giovanni Frisullo, Aldobrando Broccolini and 3 more

Abstract read
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In one paragraph

Article in Journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Beatrice RaveraUniversità Cattolica del Sacro Cuore, Rome, Italy.
Chiara LombardiUniversità Cattolica del Sacro Cuore, Rome, Italy.
Simone BellaviaUniversità Cattolica del Sacro Cuore, Rome, Italy.
Irene ScalaUniversità Cattolica del Sacro Cuore, Rome, Italy.
Fabiana CerulliUniversità Cattolica del Sacro Cuore, Rome, Italy.
Eleonora TorchiaUniversità Cattolica del Sacro Cuore, Rome, Italy.
Sara BortolaniDipartimento Di Neuroscienze, Organi Di Senso E Torace, UOC Di Neurologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, 00168, Rome, Italy.
Pier Andrea RizzoUniversità Cattolica del Sacro Cuore, Rome, Italy.
Giovanni FrisulloDipartimento Di Neuroscienze, Organi Di Senso E Torace, UOC Di Neurologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, 00168, Rome, Italy.
Aldobrando BroccoliniUniversità Cattolica del Sacro Cuore, Rome, Italy.
Giacomo Della MarcaUniversità Cattolica del Sacro Cuore, Rome, Italy.
Paolo CalabresiUniversità Cattolica del Sacro Cuore, Rome, Italy.
Mauro MonforteDipartimento Di Neuroscienze, Organi Di Senso E Torace, UOC Di Neurologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, 00168, Rome, Italy. mauro.monforte@policlinicogemelli.it.ORCID http://orcid.org/0000-0002-4327-6969

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSarcopenia, defined as the loss of skeletal muscle mass, has been associated with a worse functional outcome after stroke. Measurement of temporal muscle thickness (TMT) has been introduced as an easily obtainable surrogate marker to identify patients with sarcopenia. Our study aims to investigate the correlation between pre-stroke sarcopenia, measured by TMT assessment, and functional outcome in patients treated with revascularization procedures for acute ischemic stroke.

methodsWe included consecutive adult patients who underwent thrombolysis, endovascular thrombectomy or both for acute ischemic stroke at our Centre from January 2020 to June 2022. Besides collecting baseline clinical and neuroradiological features, TMT was measured on brain computed tomography scans according to a standardized protocol. Modified Rankin Scale (mRS) scores at 3 months represented the main endpoint of functional outcome.

resultsA total of 261 patients were available for the analysis. In univariate models, patients with excellent outcomes (mRS = 0-1) were younger, had higher TMT values and lower pre-event disability and stroke severity. In multivariate models higher TMT values resulted independently associated with reduced mortality (Odds Ratio 0.708, 95% Confidence Interval 0.538-0.930, p = 0.013). Age, diabetes, brain bleeding events and stroke severity were found to be predictors of mortality, too.

conclusionsOur retrospective analysis shows that in patients who underwent revascularization treatments for ischemic stroke TMT is as an independent predictor of survival easily obtainable from the baseline CT scan. Further investigation is required to confirm the role of sarcopenia assessment and TMT measurement in the prognostication toolkit of this disease.

Indexed as

Ischemic StrokeSarcopeniaTemporal MuscleAgedAged, 80 and overBrain IschemiaCohort StudiesEndovascular ProceduresFemaleHumansMaleMiddle AgedOutcome Assessment, Health CarePrognosisRecovery of FunctionReperfusionEndovascular thrombectomyIschemic strokeOutcomeSarcopeniaTemporalis muscle thicknessThrombolysis

Identifiers

PMID39028361

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.