Evidence map›Paper›PMID 39031228›Full record

ArticleAnalytical and bioanalytical chemistry2024

Enhancing electrochemical detection through machine learning-driven prediction for canine mammary tumor biomarker with green silver nanoparticles.

Sinem Özlem Enginler, Tarık Küçükdeniz, Gamze Evkuran Dal, Funda Yıldırım, Gökçe Erdemir Cilasun, Fulya Üstün Alkan, Hazal Öztürk Gürgen, Nevin Taşaltın, Ahmet Sabuncu, Merve Yılmaz and 1 more

Abstract read
In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sinem Özlem EnginlerDepartment of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Istanbul University-Cerrahpaşa, Avcılar, 34320, Istanbul, Turkey. enginler@iuc.edu.tr.
Tarık KüçükdenizDepartment of Industrial Engineering, Faculty of Engineering, Istanbul University-Cerrahpaşa, Avcılar, 34320, Istanbul, Turkey.
Gamze Evkuran DalDepartment of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Istanbul University-Cerrahpaşa, Avcılar, 34320, Istanbul, Turkey.
Funda YıldırımDepartment of Pathology, Faculty of Veterinary Medicine, Istanbul University-Cerrahpaşa, Buyukcekmece, 34500, Istanbul, Turkey.
Gökçe Erdemir CilasunDepartment of Molecular Medicine, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Fatih, 34104, Istanbul, Turkey.
Fulya Üstün AlkanDepartment of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Istanbul University-Cerrahpaşa, Buyukcekmece, 34500, Istanbul, Turkey.
Hazal Öztürk GürgenDepartment of Pathology, Faculty of Veterinary Medicine, Istanbul University-Cerrahpaşa, Buyukcekmece, 34500, Istanbul, Turkey.
Nevin TaşaltınDepartment of Electrical and Electronics Engineering, Faculty of Engineering and Natural Sciences, Maltepe University, Maltepe, 34857, Istanbul, Turkey.
Ahmet SabuncuDepartment of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Istanbul University-Cerrahpaşa, Avcılar, 34320, Istanbul, Turkey.
Merve YılmazDepartment of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Istanbul University-Cerrahpaşa, Avcılar, 34320, Istanbul, Turkey.
Selcan KarakuşDepartment of Chemistry, Faculty of Engineering, Istanbul University-Cerrahpaşa, Avcılar, 34320, Istanbul, Turkey. selcan@iuc.edu.tr.

Funding

Istanbul Üniversitesi-Cerrahpasa TSA-2022-36243
6 · The paper itself

Abstract

This study developed an innovative biosensor strategy for the sensitive and selective detection of canine mammary tumor biomarkers, cancer antigen 15-3 (CA 15-3) and mucin 1 (MUC-1), integrating green silver nanoparticles (GAgNPs) with machine learning (ML) algorithms to achieve high diagnostic accuracy and potential for noninvasive early detection. The GAgNPs-enhanced electrochemical biosensor demonstrated selective detection of CA 15-3 in serum and MUC-1 in tissue homogenates, with limits of detection (LODs) of 0.07 and 0.11 U mL

Indexed as

Biomarkers, TumorBiosensing TechniquesElectrochemical TechniquesMachine LearningMammary Neoplasms, AnimalMetal NanoparticlesSilverAnimalsDog DiseasesDogsFemaleLimit of DetectionMucin-1Biomarkers, TumorMucin-1SilverBiosensorCA 15–3Data scienceElectrochemistryMUC 1

Identifiers

PMID39031228
PMCPMC11377509

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.