Evidence map›Paper›PMID 39033100›Full record

ReviewJournal of neurodevelopmental disorders2024

A clinical-translational review of sleep problems in neurodevelopmental disabilities.

Sarika U Peters, Althea Robinson Shelton, Beth A Malow, Jeffrey L Neul

Abstract readReview
In one paragraph

Review in Journal of neurodevelopmental disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sarika U PetersDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, USA. sarika.u.peters@vumc.org.ORCID 0000-0001-7439-5402
Althea Robinson SheltonVanderbilt Kennedy Center for Research on Human Development, One Magnolia Circle, Room 404B, Nashville, TN, 37203, USA.
Beth A MalowDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, USA.
Jeffrey L NeulDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, USA.

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
Clinical validation of at-home methods of sleep assessment in Rett SyndromeR21TR003942 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PETERS, SARIKA U · 2021 to 2022
$458k
National Institute of Child Health and Human Development P50HD103537NCATS NIH HHS R21 TR003942NCATS NIH HHS R21TR003942NICHD NIH HHS P50 HD103537
6 · The paper itself

Abstract

Sleep disorders are very common across neurodevelopmental disorders and place a large burden on affected children, adolescents, and their families. Sleep disturbances seem to involve a complex interplay of genetic, neurobiological, and medical/environmental factors in neurodevelopmental disorders. In this review, we discuss animal models of sleep problems and characterize their presence in two single gene disorders, Rett Syndrome, and Angelman Syndrome and two more commonly occurring neurodevelopmental disorders, Down Syndrome, and autism spectrum disorders. We then discuss strategies for novel methods of assessment using wearable sensors more broadly for neurodevelopmental disorders in general, including the importance of analytical validation. An increased understanding of the mechanistic contributions and potential biomarkers of disordered sleep may offer quantifiable targets for interventions that improve overall quality of life for affected individuals and their families.

Indexed as

Neurodevelopmental DisordersSleep Wake DisordersAngelman SyndromeAnimalsAutism Spectrum DisorderDisease Models, AnimalDown SyndromeHumansRett SyndromeTranslational Research, BiomedicalAngelman syndromeAnimal modelsAutismDown syndromeNeurodevelopmental disabilitiesRett syndromeSleep

Identifiers

PMID39033100
PMCPMC11265033

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.