Evidence map›Paper›PMID 39035106›Full record

ReviewHemaSphere2024

Realizing precision medicine in chronic lymphocytic leukemia: Remaining challenges and potential opportunities.

Kostas Stamatopoulos, Sarka Pavlova, Othman Al-Sawaf, Thomas Chatzikonstantinou, Christina Karamanidou, Gianluca Gaidano, Florence Cymbalista, Arnon P Kater, Andy Rawstron, Lydia Scarfò and 2 more

Erratum issuedAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in HemaSphere, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Kostas StamatopoulosCentre for Research and Technology Hellas Institute of Applied Biosciences Thessaloniki Greece.
Sarka PavlovaDepartment of Internal Medicine, Hematology and Oncology, and Institute of Medical Genetics and Genomics University Hospital Brno and Medical Faculty, Masaryk University Brno Czech Republic.ORCID 0000-0003-1528-9743
Othman Al-SawafDepartment I of Internal Medicine and German CLL Study Group, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) University of Cologne, Faculty of Medicine and University Hospital of Cologne Cologne Germany.
Thomas ChatzikonstantinouCentre for Research and Technology Hellas Institute of Applied Biosciences Thessaloniki Greece.
Christina KaramanidouCentre for Research and Technology Hellas Institute of Applied Biosciences Thessaloniki Greece.
Gianluca GaidanoDivision of Haematology, Department of Translational Medicine University of Eastern Piedmont Novara Italy.
Florence CymbalistaUMR INSERMU978/Paris 13 University Bobigny France.
Arnon P KaterDepartment of Hematology, Cancer Center Amsterdam Amsterdam University Medical Centers, University of Amsterdam Amsterdam The Netherlands.
Andy RawstronHaematological Malignancy Diagnostic Service Leeds Teaching Hospitals Trust Leeds UK.
Lydia ScarfòMedical School Università Vita Salute San Raffaele Milano Italy.
Paolo GhiaMedical School Università Vita Salute San Raffaele Milano Italy.ORCID 0000-0003-3750-7342
Richard RosenquistDepartment of Molecular Medicine and Surgery Karolinska Institutet Stockholm Sweden.ORCID 0000-0002-0211-8788

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with chronic lymphocytic leukemia (CLL) exhibit diverse clinical outcomes. An expanding array of genetic tests is now employed to facilitate the identification of patients with high-risk disease and inform treatment decisions. These tests encompass molecular cytogenetic analysis, focusing on recurrent chromosomal alterations, particularly del(17p). Additionally, sequencing is utilized to identify

Identifiers

PMID39035106
PMCPMC11260284

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.