Evidence map›Paper›PMID 39038956›Full record

ArticleAJNR. American journal of neuroradiology2025

DANTE-CAIPI Accelerated Contrast-Enhanced 3D T1: Deep Learning-Based Image Quality Improvement for Vessel Wall MRI.

Mona Kharaji, Gador Canton, Yin Guo, Mohamad Hosaam Mosi, Zechen Zhou, Niranjan Balu, Mahmud Mossa-Basha

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Enhanced Visualization of Intracranial Cortical Arteries Using Deep Learning Reconstruction in Vessel Wall MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
    Article
  3. Article
  4. Clinical implications of vessel wall imaging-State-of-the-art review.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mona KharajiFrom the Department of Radiology (M.K., G.C., M.H.M., N.B., M.M.-B.), University of Washington School of Medicine, Seattle, Washington.
Gador CantonFrom the Department of Radiology (M.K., G.C., M.H.M., N.B., M.M.-B.), University of Washington School of Medicine, Seattle, Washington.ORCID 0000-0002-0594-2764
Yin GuoDepartment of Bioengineering (Y.G.), University of Washington, Seattle, Washington.ORCID 0000-0002-6006-9849
Mohamad Hosaam MosiFrom the Department of Radiology (M.K., G.C., M.H.M., N.B., M.M.-B.), University of Washington School of Medicine, Seattle, Washington.
Zechen ZhouSubtle Medical Inc (Z.Z.), Menlo Park, California.
Niranjan BaluFrom the Department of Radiology (M.K., G.C., M.H.M., N.B., M.M.-B.), University of Washington School of Medicine, Seattle, Washington.ORCID 0000-0002-1489-6683
Mahmud Mossa-BashaFrom the Department of Radiology (M.K., G.C., M.H.M., N.B., M.M.-B.), University of Washington School of Medicine, Seattle, Washington mmossab@uw.edu.ORCID 0000-0001-7798-8158

Funding

3D WALLI: MR intracranial vessel wall imaging for stroke preventionR01NS092207 · NINDS · UNIVERSITY OF WASHINGTON · PI MOSSA-BASHA, MAHMUD, YUAN, CHUN · 2016 to 2019
$3.1M
Quantitative model-based ESUS reclassification using cardiac and cerebral vessel wall MRIR01NS125635 · NINDS · UNIVERSITY OF WASHINGTON · PI AKOUM, NAZEM, MOSSA-BASHA, MAHMUD · 2022 to 2025
$3.0M
NINDS NIH HHS R01 NS092207NINDS NIH HHS R01 NS125635
6 · The paper itself

Abstract

background and purposeAccelerated and blood-suppressed postcontrast 3D intracranial vessel wall MRI (IVW) enables high-resolution rapid scanning but is associated with low SNR. We hypothesized that a deep-learning (DL) denoising algorithm applied to accelerated, blood-suppressed postcontrast IVW can yield high-quality images with reduced artifacts and higher SNR in shorter scan times. MATERIALS AND

methodsSixty-four consecutive patients underwent IVW, including conventional postcontrast 3D T1-sampling perfection with application-optimized contrasts by using different flip angle evolution (SPACE) and delay alternating with nutation for tailored excitation (DANTE) blood-suppressed and CAIPIRINHIA-accelerated (CAIPI) 3D T1-weighted TSE postcontrast sequences (DANTE-CAIPI-SPACE). DANTE-CAIPI-SPACE acquisitions were then denoised by using an unrolled deep convolutional network (DANTE-CAIPI-SPACE+DL). SPACE, DANTE-CAIPI-SPACE, and DANTE-CAIPI-SPACE+DL images were compared for overall image quality, SNR, severity of artifacts, arterial and venous suppression, and lesion assessment by using 4-point or 5-point Likert scales. Quantitative evaluation of SNR and contrast-to-noise ratio (CNR) was performed.

resultsDANTE-CAIPI-SPACE+DL showed significantly reduced arterial (1 [1-1.75] versus 3 [3-4],

conclusionsDL denoised postcontrast T1-weighted DANTE-CAIPI-SPACE accelerated and blood-suppressed IVW showed improved flow suppression with a shorter scan time and equivalent qualitative and quantitative SNR measures relative to conventional postcontrast IVW. It also improved SNR metrics relative to postcontrast DANTE-CAIPI-SPACE IVW. Implementing DL denoised DANTE-CAIPI-SPACE IVW has the potential to shorten protocol time while maintaining or improving the image quality of IVW.

Indexed as

Contrast MediaDeep LearningImaging, Three-DimensionalAdultAgedArtifactsFemaleHumansImage EnhancementMagnetic Resonance ImagingMaleMiddle AgedQuality ImprovementSignal-To-Noise RatioContrast Media

Identifiers

PMID39038956
PMCPMC11735441

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.