Evidence map›Paper›PMID 39042726›Full record

ArticleScience signaling2024

The kinase ITK controls a Ca

Orchi Anannya, Weishan Huang, Avery August

Abstract read
In one paragraph

Article in Science signaling, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Balancing immune activation with Itk.Trends in pharmacological sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Orchi AnannyaDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-0536-5829
Weishan HuangDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-1330-1131
Avery AugustDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-4968-3415

Funding

Small RNA Pathways in Mammalian GametogenesisP50HD076210 · NICHD · CORNELL UNIVERSITY · PI COHEN, PAULA ELAINE · 2014 to 2018
$7.4M
Regulation of IL10 production in CD8+ T cells during Flu infection by tyrosine kinase ItkR01AI138570 · NIAID · CORNELL UNIVERSITY · PI AUGUST, AVERY · 2018 to 2022
$2.1M
Itk mediated tuning of CD8+ memory T cell developmentR01AI120701 · NIAID · CORNELL UNIVERSITY · PI AUGUST, AVERY · 2016 to 2019
$1.5M
Itk signaling and Type 1 regulatory T cell differentiation and function in allergic airway inflammationR21AI129422 · NIAID · CORNELL UNIVERSITY · PI AUGUST, AVERY, HUANG, WEISHAN · 2018 to 2019
$431k
NIAID NIH HHS R01 AI120701NIAID NIH HHS R01 AI138570NIAID NIH HHS R21 AI129422NICHD NIH HHS P50 HD076210
6 · The paper itself

Abstract

The balance of proinflammatory T helper type 17 (T

Indexed as

Cell DifferentiationForkhead Transcription FactorsProtein-Tyrosine KinasesTh17 CellsT-Lymphocytes, RegulatoryAnimalsCalciumCalcium SignalingMiceMice, Inbred C57BLMice, KnockoutTOR Serine-Threonine KinasesCalciumemt protein-tyrosine kinaseForkhead Transcription FactorsFoxp3 protein, mouseProtein-Tyrosine KinasesTOR Serine-Threonine Kinases

Identifiers

PMID39042726
PMCPMC11445781

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.