Evidence map›Paper›PMID 39045423›Full record

ArticleOpen access rheumatology : research and reviews2024

Autoantibodies Serum Level and 10-Year Risk of Fractures Evaluated by FRAX

Rim Sghiri, Hana Ben Hassine, Mariam Ghozzi, Nejla El Amri, Khadija Baccouche, Rihab Sarraj, Zahid Shakoor, Adel Almogren, Elyes Bouajina

Abstract read
In one paragraph

Article in Open access rheumatology : research and reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rim Sghiri *Immunology Unit, Department of Pathology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Hana Ben Hassine *Immunology Laboratory, Farhat Hached Hospital, Sousse, Tunisia.
Mariam GhozziImmunology Laboratory, Farhat Hached Hospital, Sousse, Tunisia.
Nejla El AmriDepartment of Rheumatology, Farhat Hached Hospital, Sousse, Tunisia.
Khadija BaccoucheDepartment of Rheumatology, Farhat Hached Hospital, Sousse, Tunisia.
Rihab SarrajDepartment of Rheumatology, Farhat Hached Hospital, Sousse, Tunisia.
Zahid ShakoorImmunology Unit, Department of Pathology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Adel AlmogrenImmunology Unit, Department of Pathology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Elyes BouajinaDepartment of Rheumatology, Farhat Hached Hospital, Sousse, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: FRAX Methods: FRAX Results: Fifty-one (26.9%) RA patients had high (≥20%) 10-year risk of major osteoporosis fracture and 67 (35.4%) had high (>3%) 10-year risk of hip fracture. Among all the tested autoantibodies, only IgM RF at elevated levels was associated with high 10-year risk of major osteoporosis fracture (adjusted OR = 4.1, 95% CI = 1.5-11.3, Conclusion: Our study highlights the importance of quantitative measurement of autoantibodies in assessment of risk for fractures among RA patients. Our preliminary findings need to be assessed in prospective studies to determine the actual predictive value of high IgM RF levels among patients with RA.

Indexed as

10-years risk of hip fracture10-years risk of major osteoporosis fractureanti-cyclic citrullinated peptide antibodyanti-mutated citrullinated vimentin antibodyFRAXosteoporosisrheumatoid arthritisrheumatoid factorrheumatoid factor isotypes

Identifiers

PMID39045423
PMCPMC11265213

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.