Evidence map›Paper›PMID 39046999›Full record

ArticlePloS one2024

Stated preferences for new HIV prevention technologies among men who have sex with men in India: A discrete choice experiment.

Michael P Cameron, Peter A Newman, Venkatesan Chakrapani, Murali Shunmugam, Surachet Roungprakhon, Shruta Rawat, Dicky Baruah, Ruban Nelson, Suchon Tepjan, Riccardo Scarpa

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Michael P CameronSchool of Accounting, Finance and Economics, University of Waikato, Hamilton, New Zealand.ORCID 0000-0002-4296-3775
Peter A NewmanFactor-Inwentash Faculty of Social Work, University of Toronto, Ontario, Canada.ORCID 0000-0003-0444-5915
Venkatesan ChakrapaniCentre for Sexuality and Health Research and Policy, Chennai, India.
Murali ShunmugamCentre for Sexuality and Health Research and Policy, Chennai, India.
Surachet RoungprakhonFaculty of Science and Technology, Rajamangala University of Technology, Phra Nakhon, Bangkok, Thailand.
Shruta RawatThe Humsafar Trust, Mumbai, India.
Dicky BaruahThe Humsafar Trust, Mumbai, India.ORCID 0009-0008-8739-5012
Ruban NelsonCentre for Sexuality and Health Research and Policy, Chennai, India.
Suchon TepjanVOICES-Thailand Foundation, Chiang Mai, Thailand.
Riccardo ScarpaSchool of Accounting, Finance and Economics, University of Waikato, Hamilton, New Zealand.

Funding

DBT-Wellcome Trust India Alliance IA/CPHS/16/1/502667
6 · The paper itself

Abstract

introductionIndia has the second largest HIV epidemic in the world. Despite successes in epidemic control at the population level, a concentrated epidemic persists among gay and other men who have sex with men (MSM). However, India lags in implementation of biomedical prevention technologies, such as HIV pre-exposure prophylaxis (PrEP). In order to inform scale-up of new HIV prevention technologies, including those in the development pipeline, we assessed willingness to use oral PrEP, rectal microbicides, and HIV vaccines, and choices among product characteristics, among MSM in two major Indian cities.

methodsA cross-sectional survey was conducted with a discrete choice experiment (DCE), an established methodology for quantitively estimating end-user preferences in healthcare. Survey participants were randomly assigned to one of three questionnaire versions, each of which included a DCE for one prevention technology. Participants were recruited using chain-referral sampling by peer outreach workers, beginning with seeds in community-based organizations and public sex environments, in Chennai and Mumbai. DCE data were analyzed using random-parameters (mixed) logit (RPL) models.

resultsAmong participants (n = 600), median age was 25 years, with median monthly income of INR 9,000 (~US$125). Nearly one-third (32%) had completed a college degree and 82% were single/never married. A majority of participants (63%) reported condomless anal sex in the past month. The acceptability of all three products was universally high (≥90%). Across all three products, four attributes were significant predictors of acceptability-with efficacy consistently the most important attribute, and in decreasing order of preference, side-effects, dosing schedule, and venue. MSM varied in their preferences for product attributes in relation to their levels of education and income, and engagement in sex work and HIV risk behavior.

conclusionThis study provides empirical evidence to facilitate the integration of end users' preferences throughout design, testing, and dissemination phases of HIV prevention technologies. The findings also suggest action points and targets for interventions for diverse subgroups to support the effectiveness of combination HIV prevention among MSM in India.

Indexed as

HIV InfectionsHomosexuality, MalePre-Exposure ProphylaxisAdolescentAdultChoice BehaviorCross-Sectional StudiesHumansIndiaMaleMiddle AgedPatient PreferenceSurveys and QuestionnairesYoung Adult

Identifiers

PMID39046999
PMCPMC11268640

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.