Evidence map›Paper›PMID 39048819›Full record

ArticleNature2024

Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain.

Jennifer M Kefauver, Markku Hakala, Luoming Zou, Josephine Alba, Javier Espadas, Maria G Tettamanti, Jelena Gajić, Caroline Gabus, Pablo Campomanes, Leandro F Estrozi and 5 more

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Subtomogram Averaging of Membrane Complexes in Organelle-Derived Vesicles.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Deciphering the language of mingling lipids and proteins.Current opinion in structural biology · 2025
    Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Making PI3K superfamily enzymes run faster.Advances in biological regulation · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jennifer M KefauverDepartment of Molecular and Cellular Biology, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-6818-4673
Markku HakalaDepartment of Biochemistry, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-3485-6080
Luoming ZouDepartment of Molecular and Cellular Biology, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-7386-5350
Josephine AlbaDepartment of Biology, University of Fribourg, Fribourg, Switzerland.
Javier EspadasDepartment of Biochemistry, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-4559-5410
Maria G TettamantiDepartment of Molecular and Cellular Biology, University of Geneva, Geneva, Switzerland.
Jelena GajićDepartment of Molecular and Cellular Biology, University of Geneva, Geneva, Switzerland.
Caroline GabusDepartment of Molecular and Cellular Biology, University of Geneva, Geneva, Switzerland.
Pablo CampomanesDepartment of Biology, University of Fribourg, Fribourg, Switzerland.ORCID 0000-0001-9229-8323
Leandro F EstroziInstitut de Biologie Structurale, Université Grenoble Alpes, CEA, CNRS, IBS, Grenoble, France.ORCID 0000-0003-2548-2547
Nesli E SenDepartment of Molecular and Cellular Biology, University of Geneva, Geneva, Switzerland.
Stefano VanniDepartment of Biology, University of Fribourg, Fribourg, Switzerland.ORCID 0000-0003-2146-1140
Aurélien RouxDepartment of Biochemistry, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-6088-0711
Ambroise DesfossesInstitut de Biologie Structurale, Université Grenoble Alpes, CEA, CNRS, IBS, Grenoble, France.ORCID 0000-0002-6525-5042
Robbie LoewithDepartment of Molecular and Cellular Biology, University of Geneva, Geneva, Switzerland. Robbie.Loewith@unige.ch.ORCID 0000-0002-2482-603X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological membranes are partitioned into functional zones termed membrane microdomains, which contain specific lipids and proteins

Indexed as

Cryoelectron MicroscopyMembrane MicrodomainsSaccharomyces cerevisiaeMembrane LipidsModels, MolecularMolecular Dynamics SimulationPhosphatidylserinesPhosphoproteinsProtein DomainsSaccharomyces cerevisiae ProteinsSterolsStress, MechanicalLSP1 protein, S cerevisiaeMembrane LipidsPhosphatidylserinesPhosphoproteinsPIL1 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsSterols

Identifiers

PMID39048819
PMCPMC11324527

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.