Evidence map›Paper›PMID 39051219›Full record

ArticleNeurology international2024

Multiple Administration of Dexamethasone Possesses a Deferred Long-Term Effect to Glycosylated Components of Mouse Brain.

Stanislav D Aladev, Dmitry K Sokolov, Anastasia V Strokotova, Galina M Kazanskaya, Alexander M Volkov, Svetlana V Aidagulova, Elvira V Grigorieva

Abstract read
In one paragraph

Article in Neurology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stanislav D AladevInstitute of Molecular Biology and Biophysics FRC FTM, Novosibirsk 630117, Russia.ORCID 0000-0001-5883-4831
Dmitry K SokolovInstitute of Molecular Biology and Biophysics FRC FTM, Novosibirsk 630117, Russia.ORCID 0000-0002-4145-5277
Anastasia V StrokotovaInstitute of Molecular Biology and Biophysics FRC FTM, Novosibirsk 630117, Russia.ORCID 0000-0001-5336-8552
Galina M KazanskayaInstitute of Molecular Biology and Biophysics FRC FTM, Novosibirsk 630117, Russia.
Alexander M VolkovE.N. Meshalkin National Medical Research Center, Novosibirsk 630055, Russia.
Svetlana V AidagulovaInstitute of Molecular Biology and Biophysics FRC FTM, Novosibirsk 630117, Russia.ORCID 0000-0001-7124-1969
Elvira V GrigorievaInstitute of Molecular Biology and Biophysics FRC FTM, Novosibirsk 630117, Russia.ORCID 0000-0003-2457-9179

Funding

Russian Science Foundation № 21-15-00285
6 · The paper itself

Abstract

Glucocorticoids are used during glioblastoma treatment to prevent the cerebral edema effect surrounding normal brain tissue. The aim of our study was to investigate the long-term effects of multiple administrations of glucocorticoids onto the glycosylated components (proteoglycans and glycosaminoglycans) of normal brain extracellular matrix and the glucocorticoid receptor (GR,

Indexed as

brain extracellular matrixdexamethasoneglucocorticoidglucocorticoid receptorglycosaminoglycanglycosylationheparan sulfate biosynthesisproteoglycan

Identifiers

PMID39051219
PMCPMC11270268

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.