Evidence mapPaperPMID 39051852Full record

ReviewCell proliferation2024

Endothelial progenitor cells for fabrication of engineered vascular units and angiogenesis induction.

Somayyeh Rashidi, Ghasem Bagherpour, Zahra Abbasi-Malati, Nafiseh Didar Khosrowshahi, Sara Aghakhani Chegeni, Golbarg Roozbahani, Hamid Lotfimehr, Emel Sokullu, Reza Rahbarghazi

Abstract readReview
In one paragraph

Review in Cell proliferation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  9. Melatonin and angiogenesis potential in stem cells.Stem cell research & therapy · 2025
    Review
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Somayyeh RashidiDepartment of Medical Biotechnology, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Ghasem BagherpourDepartment of Medical Biotechnology, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Zahra Abbasi-MalatiStudent Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Nafiseh Didar KhosrowshahiChemical Engineering Faculty, Sahand University of Technology, Tabriz, Iran.
Sara Aghakhani ChegeniDepartment of Clinical Biochemistry and Laboratory Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Golbarg RoozbahaniDepartment of Plant, Cell and Molecular Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.
Hamid LotfimehrStem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Emel SokulluResearch Center for Translational Medicine (KUTTAM), Koç University, Istanbul, Turkey.
Reza RahbarghaziStem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0003-3864-9166

Funding

Tabriz University of Medical Sciences 72512, EthicalcodeTabriz University of Medical Sciences IR.TBZMED.AEC.1402.084Zanjan University of Medical Sciences 5759Zanjan University of Medical Sciences EthicalcodeZanjan University of Medical Sciences IR.ZUMS.AEC.1402.014
6 · The paper itself

Abstract

The promotion of vascularization and angiogenesis in the grafts is a crucial phenomenon in the healing process and tissue engineering. It has been shown that stem cells, especially endothelial progenitor cells (EPCs), can stimulate blood vessel formation inside the engineered hydrogels after being transplanted into the target sites. The incorporation of EPCs into the hydrogel can last the retention time, long-term survival, on-target delivery effects, migration and differentiation into mature endothelial cells. Despite these advantages, further modifications are mandatory to increase the dynamic growth and angiogenesis potential of EPCs in in vitro and in vivo conditions. Chemical modifications of distinct composites with distinct physical properties can yield better regenerative potential and angiogenesis during several pathologies. Here, we aimed to collect recent findings related to the application of EPCs in engineered vascular grafts and/or hydrogels for improving vascularization in the grafts. Data from the present article can help us in the application of EPCs as valid cell sources in the tissue engineering of several ischemic tissues.

Indexed as

Endothelial Progenitor CellsHydrogelsNeovascularization, PhysiologicTissue EngineeringAngiogenesisAnimalsBlood Vessel ProsthesisCell DifferentiationHumansHydrogels

Identifiers

PMID39051852
PMCPMC11503262

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.