SynthesisBMC oral health2024
Is routine antibiotic prophylaxis warranted in dental implant surgery to prevent early implant failure? - a systematic review.
Synthesis in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Global prevalence and guideline adherence of antibiotic prescribing in dental implant surgery: A systematic review and meta-analysis.The Japanese dental science review · 2026Review
- Consensus Statement on Full-Arch Implant Rehabilitations: Evidence-Based Recommendations from the Italian Consensus Conference.Journal of clinical medicine · 2026Article
- Surgical factors related to dental implant failure: A cross-sectional multicentre study on 1,308 dental implants.Medicina oral, patologia oral y cirugia bucal · 2026Article
- Review
- Rational utilization of antibiotic prophylaxis in oral and maxillofacial surgery: a large scope review of recent data.BMC oral health · 2025Review
- Antibiotic prophylaxis in dental implant surgery - A qualitative study on the attitudes and routines of Swedish dentists.BMC oral health · 2025Article
- Effect of Antibiotic Prophylaxis in Dental Implant Surgery: A Randomized Controlled Clinical Trial.Dentistry journal · 2025Article
- Effect of preoperative antibiotic use on the implant success rate: a retrospective cohort study of cefixime and ornidazole in China.BMC oral health · 2025Article
- Use of antibiotic prophylaxis in conjunction with dental implant surgery in Sweden- A cross-sectional study.BMC oral health · 2025Article
- An Assessment of the Knowledge and Attitudes of Final-Year Dental Students on and Towards Antibiotic Use: A Questionnaire Study.Antibiotics (Basel, Switzerland) · 2025Article
- Antibiotic Prophylaxis Prescribing Practices for Dental Implant Placement in Croatia: A Questionnaire-Based Cross-Sectional Study.Antibiotics (Basel, Switzerland) · 2025Article
- Routine antibiotic prophylaxis and early implant failure: is there a link?Evidence-based dentistry · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe question of whether antibiotic prophylaxis should be administered routinely for dental implant surgery is unresolved. Despite the lack of conclusive supportive evidence, antibiotics are often administered to reduce the risk of infection, which could lead to early implant failure. Increasing antibiotic resistance is a major concern and it is therefore important to reduce the overall use of antibiotics, including in dentistry. The aim of the present systematic review and meta-analysis was to evaluate the efficacy of preoperative antibiotics in preventing early implant failure, in overall healthy patients undergoing dental implant surgery.
methodsAn electronic search was undertaken of PubMed (Medline), Web of Science and the Cochrane Library up to October 1
resultsAfter removal of duplicates, 1086 abstracts were screened, and 17 articles were reviewed in full text. Seven RCTs with moderate or low risk of bias and with a total of 1859 patients and 3014 implants were included in the meta-analysis. With reference to early implant failure at patient level, the meta-analysis failed to disclose any statistically significant difference (RR: 0.66, 95% CI: 0.30-1.47) between antibiotic prophylaxis and a placebo. The risk difference was -0.007 (95% CI: -0.035-0.020) leading to a number needed to treat (NNT) of 143.
conclusionAntibiotic prophylaxis for dental implant surgery does not seem to have any substantial effect on early implant failure ( ). The results do not support routine antibiotic prophylaxis for dental implant surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.