Evidence map›Paper›PMID 39055244›Full record

ReviewKardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery2024

Left main coronary artery disease: percutaneous coronary intervention or coronary artery bypass grafting? A critical review of current knowledge and contemporary debates.

Ioannis Panagiotopoulos, Francesk Mulita, Georgios-Ioannis Verras, Eleni Bekou, Admir Mulita, Manfred Dahm, Konstantinos Grapatsas, Assaf Sawafta, Anastasia Katinioti, Elias Liolis and 7 more

Abstract readReview
In one paragraph

Review in Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ioannis PanagiotopoulosDepartment of Cardiothoracic Surgery, General University Hospital of Patras, Patras, Greece.
Francesk MulitaDepartment of Surgery, General University Hospital of Patras, Patras, Greece.
Georgios-Ioannis VerrasDepartment of Surgery, General University Hospital of Patras, Patras, Greece.
Eleni BekouMedical Physics Department, Democritus University of Thrace, University Hospital of Alexandroupolis, Alexandroupolis, Greece.
Admir MulitaMedical Physics Department, Democritus University of Thrace, University Hospital of Alexandroupolis, Alexandroupolis, Greece.
Manfred DahmDepartment of Cardiothoracic and Vascular Surgery, Westpfalz Klinikum, Kaiserslautern, Germany.
Konstantinos GrapatsasDepartment of Thoracic Surgery and Thoracic Endoscopy, Ruhrlandklinik, West German Lung Center, University Hospital Essen, University Duisburg-Essen Essen, Germany.
Assaf SawaftaDepartment of Cardiology, University Hospital of Larissa, Larissa, Greece.
Anastasia KatiniotiCardiology Department, Elpis General Hospital, Athens, Greece.
Elias LiolisDepartment of Oncology, General University Hospital of Patras, Patras, Greece.
Christos PitrosDepartment of Vascular Surgery, General University Hospital of Patras, Patras, Greece.
Levan TchabashviliDepartment of Surgery, General University Hospital of Patras, Patras, Greece.
Konstantinos TasiosDepartment of Surgery, General University Hospital of Patras, Patras, Greece.
Andreas AntzoulasDepartment of Surgery, General University Hospital of Patras, Patras, Greece.
Spyros PapadoulasDepartment of Vascular Surgery, General University Hospital of Patras, Patras, Greece.
Efstratios KoletsisDepartment of Cardiothoracic Surgery, General University Hospital of Patras, Patras, Greece.
Vasileios LeivaditisDepartment of Cardiothoracic and Vascular Surgery, Westpfalz Klinikum, Kaiserslautern, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significant unprotected left main (ULM) disease is the highest-risk coronary artery lesion, carries high morbidity and mortality related to a large amount of myocardium supplied, and should undergo prompt revascularization. Among recent randomized controlled trials (RCTs), NOBLE failed to demonstrate non-inferiority of percutaneous coronary intervention (PCI) versus coronary artery bypass grafting (CABG). However, all the other RCTs have shown comparable outcomes. While CABG is associated with higher stroke rates at 30 days and 1 year, PCI is associated with increased spontaneous myocardial infarction (MI) events and the need for repeat revascularization. Furthermore, the benefit of CABG is more evident with the increased complexity of coronary artery disease. In current European and American guidelines, CABG is the standard of care for ULM disease. PCI is considered a reasonable alternative in selected patients (2a B-NR). There is still a great need for carefully designed RCTs with longer follow-up times to validate the role of recent technological and pharmacological regimens.

Indexed as

contemporary debatescoronary artery bypass graftingleft main coronary artery diseasepercutaneous coronary intervention

Identifiers

PMID39055244
PMCPMC11267640

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.