ReviewJournal of the American Heart Association2024
Frailty and Cardiovascular Health.
Review in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
75 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- National Heart Center/Saudi Heart Association 2025 Guidelines for Cardiovascular Diseases Prevention and Risk Assessment.Saudi medical journal · 2026Guideline
- Prevalence and risk factors of frailty among cardiac surgery patients: a systematic review and meta-analysis.Annals of medicine · 2025Pooled it
- A meta-synthesis of qualitative studies on cardiovascular disease patients' experiences using digital health tools.Frontiers in public health · 2025Pooled it
- Assessing Frailty-Specific Treatment Effect in Cardiovascular Disease: A Systematic Review.Drugs & aging · 2024Pooled it
- The Impact of Additional Exercise Interventions on Physical Performance and Muscle Strength of Frail Patients After Open-Heart Surgery: A Randomized Trial.Medicina (Kaunas, Lithuania) · 2025Trial
- The Impact of Dental Prostheses in Patients With Cardiovascular Disease: A Scoping Review With Exploratory Analysis.International dental journal · 2026Article
- Established and emerging roles of lysosomal dysfunction in cardiac aging.Nature cardiovascular research · 2026Review
- Frailty Index and Risk of Ischemic Stroke in China: Evidence from a Cohort Study, Disease Burden Analysis, and Mendelian Randomization.Healthcare (Basel, Switzerland) · 2026Article
- The prevalence of frailty and associated factors in patients with type 2 diabetes mellitus and coronary heart disease: A cross-sectional study.Journal of diabetes investigation · 2026Article
- Nutritional Status and Cardiovascular Disease in Older Adults: Clinical Perspectives from Mechanisms to Management.Journal of clinical medicine · 2026Review
- Clinical outcomes after catheter ablation for atrial fibrillation in elderly patients: a meta-analysis with time-to-event data reconstruction.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Review
- The Living Lab Concept in the Detection, Prevention and Monitoring of Geriatric Syndromes in Elderly Patients with Cardiovascular Disease-A Narrative Review.Journal of clinical medicine · 2026Review
- Frailty and Echocardiographic Indices of Diastolic Function in Older Adults: A Cross-Sectional Analysis.Journal of clinical medicine · 2026Article
- Statins and survival free of incident frailty among older US veterans.European heart journal · 2026Article
- Frailty and long-term outcomes in younger patients with acute myocardial infarction.European heart journal · 2026Article
- Optimizing cardiovascular pharmacotherapy in older adults with frailty.Nature reviews. Cardiology · 2026Review
- The ABCs of cardiovascular disease prevention: communicating what we know in 2026.American journal of preventive cardiology · 2026Review
- Frailty and Cardiovascular Events as Determined by Body Composition: A Systematic Review.Chronic diseases and translational medicine · 2026Review
- Frailty as a predictor of adverse in-hospital outcomes in older patients with Takotsubo cardiomyopathy.Journal of geriatric cardiology : JGC · 2026Article
- Plasma metabolomic and inflammatory profiles associated with low physical function in heart failure: an integrated cardiac-metabolic-muscular phenotype.GeroScience · 2026Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
The incidence of frailty and cardiovascular disease (CVD) increases as the population ages. There is a bidirectional relationship between frailty and CVD, and both conditions share several risk factors and underlying biological mechanisms. Frailty has been established as an independent prognostic marker in patients with CVD. Moreover, its presence significantly influences both primary and secondary prevention strategies for adults with CVD while also posing a barrier to the inclusion of these patients in pivotal clinical trials and advanced cardiac interventions. This review discusses the current knowledge base on the relationship between frailty and CVD, how managing CVD risk factors can modify frailty, the influence of frailty on CVD management, and future directions for frailty detection and modification in patients with CVD.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.