Evidence map›Paper›PMID 39056982›Full record

ArticleDentistry journal2024

A Synthetic Small Molecule, LGM2605: A Promising Modulator of Increased Pro-Inflammatory Cytokine and Osteoclast Differentiation by

Taewan J Kim, Andrew S MacElroy, Aleena Defreitas, Bruce J Shenker, Kathleen Boesze-Battaglia

Abstract read
In one paragraph

Article in Dentistry journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Taewan J KimDepartment of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-7100-4576
Andrew S MacElroyDepartment of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Aleena DefreitasDepartment of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Bruce J ShenkerDepartment of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Kathleen Boesze-BattagliaDepartment of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-0962-0508

Funding

A. Actinomycetemcomitans Cdt Induces Pro-Inflammatory Innate Immune ResponsesR01DE023071 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI BOESZE-BATTAGLIA, KATHLEEN, SHENKER, BRUCE J · 2013 to 2024
$4.6M
Cytolethal distending toxin mediated modulation of phagocytic functionK08DE032119 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI KIM, TAEWAN JOHN · 2022 to 2025
$484k
NIDCR NIH HHS K08 DE032119NIDCR NIH HHS R01 DE023071
6 · The paper itself

Abstract

Our research explores the interplay between

Indexed as

anti-inflammationflaxseedlocalized aggressive periodontitismolar/incisor patternosteoclastsmall molecule therapeutic

Identifiers

PMID39056982
PMCPMC11276599

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.